Title:
ACAT INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2008/015950
Kind Code:
A1
Abstract:
An acyl-CoA cholesterol acyltransferase inhibitor comprising at least one member selected from the group consisting of 3'-acetoxy-4'-tigloyloxy-3'-4'-dihydroseselin, a derivative thereof and a pharmaceutically acceptable salt of the compound or the derivative as an active ingredient. The inhibitor or a pharmaceutical, food or animal feed comprising the inhibitor is effective for hyperlipemia, arterial sclerosis or a disease associated with these diseases. Particularly, the food is useful as a functional food which has an inhibitory activity on acyl-CoA cholesterol acyltransferase and is effective for the maintenance of homeostasis in vivo.
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Inventors:
ENOKI TATSUJI
TAKASHIMA FUYUKO
OHNOGI HIROMU
KATO IKUNOSHIN
TAKASHIMA FUYUKO
OHNOGI HIROMU
KATO IKUNOSHIN
Application Number:
PCT/JP2007/064634
Publication Date:
February 07, 2008
Filing Date:
July 26, 2007
Export Citation:
Assignee:
TAKARA BIO INC (JP)
ENOKI TATSUJI
TAKASHIMA FUYUKO
OHNOGI HIROMU
KATO IKUNOSHIN
ENOKI TATSUJI
TAKASHIMA FUYUKO
OHNOGI HIROMU
KATO IKUNOSHIN
International Classes:
C07D493/04; A23K1/16; A23L1/30; A61K31/37; A61K36/23; A61P3/06; A61P9/10; A61P43/00
Domestic Patent References:
| WO2005074906A1 | 2005-08-18 | |||
| WO2006082743A1 | 2006-08-10 |
Attorney, Agent or Firm:
HOSODA, Yoshinori (P.O. Box 26 OMM Building 5th Floor,7-31, Otemae 1-chome, Chuo-ku,Osaka-sh, Osaka 91, JP)
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