Title:
ACTIVATED LYMPHOCYTES COMPRISING CYTOKINE-INDUCED KILLER CELLS AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2020/231058
Kind Code:
A1
Abstract:
The present invention relates to activated lymphocytes comprising cytokine-induced killer cells in which CD8+CD56+NKG2D+ cells are present at a proportion of 20% or higher, and a preparation method therefor and, more particularly, to activated lymphocytes comprising cytokine-induced killing cells which have high tumor cell killing abilities and growth rates and are almost free of side effects because they do not require the combined administration of interleukin-2, and a preparation method therefor.
Inventors:
JUNG GYOU CHUL (KR)
KIM DONG YOUNG (KR)
LEE JI MIN (KR)
KIM DONG YOUNG (KR)
LEE JI MIN (KR)
Application Number:
PCT/KR2020/005896
Publication Date:
November 19, 2020
Filing Date:
May 04, 2020
Export Citation:
Assignee:
GREENCROSSCELL (KR)
International Classes:
C12N5/078; A61K35/14; A61P35/00
Foreign References:
| KR20080018089A | 2008-02-27 | |||
| KR20180032366A | 2018-03-30 | |||
| KR20090127973A | 2009-12-15 |
Other References:
VICTORIA LOUISE REID; MCDONALD RACHAEL; NWOSU AMARA CALLISTUS; MASON STEPHEN R; PROBERT CHRIS; ELLERSHAW JOHN E; COYLE SÉAMUS: "Phenotypic characterization and anticancer capacity of CD 8+ cytokine-induced killer cells after antigen-induced expansion", PLOS ONE, vol. 12, no. 4, e0175704, 2017, pages 1 - 31, XP055619718, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0175123
CAPPUZZELLO ELISA; SOMMAGGIO ROBERTA; ZANOVELLO PAOLA; ROSATO ANTONIO: "Cytokines for the induction of antitumor effectors: The paradigm ofCytokine-Induced Killer (CIK) cells", CYTOKINE & GROWTH FACTOR REVIEWS, vol. 36, 3 June 2017 (2017-06-03), pages 99 - 105, XP085177637, ISSN: 1359-6101, DOI: 10.1016/j.cytogfr.2017.06.003
CAPPUZZELLO ELISA; SOMMAGGIO ROBERTA; ZANOVELLO PAOLA; ROSATO ANTONIO: "Cytokines for the induction of antitumor effectors: The paradigm ofCytokine-Induced Killer (CIK) cells", CYTOKINE & GROWTH FACTOR REVIEWS, vol. 36, 3 June 2017 (2017-06-03), pages 99 - 105, XP085177637, ISSN: 1359-6101, DOI: 10.1016/j.cytogfr.2017.06.003
Attorney, Agent or Firm:
LEECHAE INTELLECTUAL PROPERTY (KR)
Download PDF:
Previous Patent: DUAL BAND ANTENNA AND ELECTRONIC DEVICE INCLUDING THE SAME
Next Patent: ACTIVATED LYMPHOCYTE AND PREPARATION METHOD THEREFOR
Next Patent: ACTIVATED LYMPHOCYTE AND PREPARATION METHOD THEREFOR