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Title:
ACTIVATORS OF HEXOSAMINE BIOSYNTHESIS AS INHIBITORS OF INJURY INDUCED BY ISCHEMIA OR HEMORRHAGIC SHOCK
Document Type and Number:
WIPO Patent Application WO2006016904
Kind Code:
A3
Abstract:
Described herein are compositions and methods for preserving cell, tissue, or organ transplants and cultures by increasing the concentration of an intracellular metabolite of the hexosamine biosynthetic pathway. Also described herein are methodsof reducing pathogenic effects in a subject by increasing the concentration of an intracellular metabolite of the hexosamine biosynthetic pathway.

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Inventors:
MARCHASE RICHARD (US)
BOUNELIS PAM (US)
CHATHAM JOHN (US)
CHAUDRY IRSHAD (US)
PANG YI (US)
Application Number:
PCT/US2005/012547
Publication Date:
August 10, 2006
Filing Date:
April 14, 2005
Export Citation:
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Assignee:
UAB RESEARCH FOUNDATION (US)
MARCHASE RICHARD (US)
BOUNELIS PAM (US)
CHATHAM JOHN (US)
CHAUDRY IRSHAD (US)
PANG YI (US)
International Classes:
A61K31/70; A01N43/04
Foreign References:
US6479469B22002-11-12
US6063911A2000-05-16
Other References:
See also references of EP 1734821A4
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