ACUTE PHARMACOLOGIC AUGMENTATION OF PSYCHOTHERAPY WITH ENHANCERS OF LEARNING OR CONDITIONING

WIPO Patent Application WO2002078629

A3

Methods for treating an individual with a psychiatric order with a pharmacologic agent that enhances learning or conditioning in combination with a session of psychotherapy are provided. These methods of the invention encompass a variety of methods of psychotherapy, and psychodynamically oriented psychotherapy, and psychiatric orders including fear and anxiety disorders, addictive disorders, addictive disorders including substance-abuse disorders, and mood disorders. The pharmacologic agents used for the methods of the present invention are ones that generally enhance learning or conditioning, including those that increase the level of norepinephrine in the brain, those that increase the level of acetylcholine in the brain, and those that enhance N-methyl-D-aspartate(NMDA) receptor transmission in the brain.

WO/1997/035864	PHOSPHORAMIDATES AND PHOSPHINIC AMIDES, THEIR USE TO MODULATE THE ACTIVITY OF ENDOTHELIN
WO/1997/035861	AZASPIRO DERIVATIVES
WO/1998/013032	COMPOSITIONS OF THERAPEUTIC AGENTS SUITABLE FOR ORAL ADMINISTRATION

DAVIS MICHAEL (US)
LU KWOK-TUNG (US)
RESSLER KERRY J (US)

PCT/US2002/009467

November 28, 2002

March 28, 2002

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UNIV EMORY (US)
DAVIS MICHAEL (US)
LU KWOK-TUNG (US)
RESSLER KERRY J (US)

A61K31/00; A61K31/132; A61K31/135; A61K31/137; A61K31/165; A61K31/198; A61K31/215; A61K45/00; A61K31/381; A61K31/42; A61K31/421; A61K31/445; A61K31/4458; A61K31/535; A61K31/5375; A61P25/18; A61P25/20; A61P25/22; A61P25/30; A61P43/00; (IPC1-7): A01N43/80; A01N33/02; A01N53/00; A61K31/42; A61K31/135; A61K31/215; A61K31/535

US5523323A	1996-06-04
US6184222B1	2001-02-06
US6333357B1	2001-12-25

See also references of EP 1383465A4

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