ADENOVIRUS VECTOR - KOLON LIFE SCIENCE INC

Title:

ADENOVIRUS VECTOR

Document Type and Number:

WIPO Patent Application WO/2021/149964

Kind Code:

A1

Abstract:

The present invention relates to an adenovirus vector having a large foreign gene loading capacity, due to deletion of a specific partial base in the E2B region, thereby being capable of carrying a large foreign gene, and having a low probability of generating a replicable adenovirus and excellent genetic stability.

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Inventors:

LEE JUN SUB (KR)
WON JEONG TAEK (KR)
SHIN YU BIN (KR)

Application Number:

PCT/KR2021/000442

Publication Date:

July 29, 2021

Filing Date:

January 13, 2021

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Assignee:

KOLON LIFE SCIENCE INC (KR)

International Classes:

C12N15/86

Foreign References:

US5994132A	1999-11-30
KR20170098947A	2017-08-30
KR20180101529A	2018-09-12
KR20190039140A	2019-04-10

Other References:

AMALFITANO, A: "Production and Characterization of Improved Adenovirus Vectors with the E1, E2b, and E3 Genes Deleted", JOURNAL OF VIROLOGY, vol. 72, no. 2, 1 February 1998 (1998-02-01), US, pages 926 - 933, XP000857441, ISSN: 0022-538X

Attorney, Agent or Firm:

LEECHAE INTELLECTUAL PROPERTY (KR)

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