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Title:
ADHESION PREVENTING COMPOSITION, SOLID PREPARATION AND METHOD FOR PRODUCING SAME
Document Type and Number:
WIPO Patent Application WO2010110321
Kind Code:
A1
Abstract:
A gel-forming layer (4) covering a drug-containing part (2) is covered with an adhesion preventing layer (5) by applying an adhesion preventing composition, which contains a water-soluble cellulose ether (such as HPMC) and an anionic polymer (such as a carboxyvinyl polymer), to the gel-forming layer (4), so that a preparation (1) is prevented from adhering to the inner wall of the oral cavity. The gel-forming layer (4) can be formed from a gel-forming agent (a carboxyvinyl polymer), a crosslinking agent, and a base agent (a polyvinyl alcohol or the like). In addition, an adhesive layer (3) may be interposed between the drug-containing part (2) and the gel-forming layer (4).

Inventors:
SUGIURA YUSAKU (JP)
TAKANO YOUICHI (JP)
Application Number:
PCT/JP2010/055093
Publication Date:
September 30, 2010
Filing Date:
March 24, 2010
Export Citation:
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Assignee:
LINTEC CORP (JP)
ASKA PHARM CO LTD (JP)
SUGIURA YUSAKU (JP)
TAKANO YOUICHI (JP)
International Classes:
A61K47/38; A61K9/24; A61K9/70; A61K47/32
Domestic Patent References:
WO2009119290A12009-10-01
WO2009072572A12009-06-11
WO2008126488A12008-10-23
WO2002087622A12002-11-07
WO1993006821A11993-04-15
WO2002087622A12002-11-07
Foreign References:
JP2008037794A2008-02-21
JP2007254340A2007-10-04
JP2006160617A2006-06-22
JPH02178222A1990-07-11
JP2002534373A2002-10-15
JP2008037794A2008-02-21
Other References:
See also references of EP 2412386A4
Attorney, Agent or Firm:
KUWATA MITSUO (JP)
Atsuo Kuwata (JP)
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