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Title:
APPETITE−STIMULATING AGENTS AND REMEDIES FOR ANOREXIA
Document Type and Number:
WIPO Patent Application WO/2003/022272
Kind Code:
A1
Abstract:
Appetite−stimulating agents containing as the active ingredient sulfonamide or sulfonic ester derivatives represented by the general formula (I), pharmacologically acceptable salts thereof, or hydrates of both: (I) wherein A is an optionally substituted mono− or bi−cyclic aromatic ring&semi B is an optionally substituted six−membered unsaturated hydrocarbon ring or an unsaturated six−membered heterocycle containing one nitrogen atom&semi C is an optionally substituted five−membered heterocycle containing one or two nitrogen atoms&semi W is a single bond or −CH=CH−&semi X is −N(R1)− or oxygen&semi Y is carbon or nitrogen&semi Z is −N(R2)− or nitrogen&semi and R1 and R2 are each independently hydrogen or lower alkyl.

Inventors:
OWA TAKASHI (JP)
OZAWA YOICHI (JP)
HIDA TAKAYUKI (JP)
MIYAMOTO NORIMASA (JP)
NAGASU TAKESHI (JP)
OKAUCHI TATSUO (JP)
YOSHINO HIROSHI (JP)
HATA NAOKO (JP)
YOSHIMATSU KENTARO (JP)
KOYANAGI NOZOMU (JP)
KITO KYOSUKE (JP)
Application Number:
PCT/JP2002/009031
Publication Date:
March 20, 2003
Filing Date:
September 05, 2002
Export Citation:
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Assignee:
EISAI C0 LTD (JP)
OWA TAKASHI (JP)
OZAWA YOICHI (JP)
HIDA TAKAYUKI (JP)
MIYAMOTO NORIMASA (JP)
NAGASU TAKESHI (JP)
OKAUCHI TATSUO (JP)
YOSHINO HIROSHI (JP)
HATA NAOKO (JP)
YOSHIMATSU KENTARO (JP)
KOYANAGI NOZOMU (JP)
KITO KYOSUKE (JP)
International Classes:
A23L1/30; A61K31/4035; A61P1/14; A61P35/00; A61P43/00; C07D209/08; C07D209/12; C07D209/30; C07D209/34; C07D209/42; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D409/14; C07D417/12; C07D471/04; (IPC1-7): A61K31/404; A61K31/4178; A61K31/427; A61K31/4439; A61K45/00; A61P1/14; A61P35/00; A61P43/00; C07D209/08; C07D209/30; C07D209/34; C07D209/42; C07D231/56; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D409/14; C07D417/12; C07D471/04
Domestic Patent References:
WO2000050395A12000-08-31
WO1999051574A11999-10-14
WO1998027081A11998-06-25
WO1998015530A11998-04-16
Foreign References:
JP2000309534A2000-11-07
Other References:
See also references of EP 1433479A4
Attorney, Agent or Firm:
Toyama, Tsutomu (4-10 Higashi Nihonbashi 3-chom, Chuo-ku Tokyo, JP)
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