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Title:
AGENTS FOR TREATMENT OF ALCOHOL USE DISORDER
Document Type and Number:
WIPO Patent Application WO/2020/030843
Kind Code:
A3
Abstract:
The present invention relates to the use of PPARα agonist compounds for preventing, alleviating, improving and/or treating alcohol use disorder.

Inventors:
RODRÍGUEZ DE FONSECA FERNANDO (ES)
DECARA DEL OLMO JUAN (ES)
SERRANO CRIADO ANTONIA (ES)
ALEN FARIÑAS FRANCISCO (ES)
Application Number:
PCT/ES2019/070565
Publication Date:
April 16, 2020
Filing Date:
August 12, 2019
Export Citation:
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Assignee:
SERVICIO ANDALUZ DE SALUD (ES)
International Classes:
A61K31/05; A61P25/32; A61K31/41
Domestic Patent References:
WO2004034968A22004-04-29
WO2006029349A12006-03-16
Foreign References:
US20090048232A12009-02-19
Other References:
BLEDNOV YURI A ET AL.: "PPAR Agonists: I. Role of Receptor Subunits in Alcohol Consumption in Male and Female Mice", ALCOHOLISM CLINICAL AND EXPERIMENTAL RESEARCH MAR 2016, vol. 40, no. 3, 29 February 2016 (2016-02-29), pages 553 - 562, XP055700896, ISSN: 0145-6008, DOI: 10.1111/acer.12976
BALLA ANDREA ET AL.: "Cannabinoid-1 receptor neutral antagonist reduces binge-like alcohol consumption and alcohol-induced accumbal dopaminergic signaling", NEUROPHARMACOLOGY, vol. 131, 15 March 2018 (2018-03-15), pages 200 - 208, XP085351311, ISSN: 0028-3908, DOI: 10.1016/j.neuropharm.2017.10.040
BLEDNOV YURI A ET AL.: "Peroxisome Proliferator-Activated Receptors alpha and gamma are Linked with Alcohol Consumption in Mice and Withdrawal and Dependence in Humans", ALCOHOLISM CLINICAL AND EXPERIMENTAL RESEARCH JAN 2015, vol. 39, no. 1, 31 December 2014 (2014-12-31), pages 136 - 145, XP055700904, ISSN: 0145-6008, DOI: 10.1111/acer.12610
Attorney, Agent or Firm:
FUSTER, Gustavo (ES)
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