Title:
AGONIST OF 67 KDA LAMININ RECEPTOR AND UTILIZATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/026302
Kind Code:
A1
Abstract:
An agonist of 67 kDa laminin receptor, said agonist comprising as an active ingredient oolong tea polymerized polyphenols or a derivative thereof.
Inventors:
TACHIBANA HIROFUMI (JP)
Application Number:
PCT/JP2017/041248
Publication Date:
February 07, 2019
Filing Date:
November 16, 2017
Export Citation:
Assignee:
UNIV KYUSHU NAT UNIV CORP (JP)
International Classes:
A61K31/353; A61P3/04; A61P3/06; A61P7/02; A61P9/10; A61P21/00; A61P29/00; A61P35/00; A61P35/02; A61P37/04; A61P37/08; A61P43/00; A23L33/105; C12N15/09
Domestic Patent References:
| WO2011162320A1 | 2011-12-29 | |||
| WO2015199169A1 | 2015-12-30 | |||
| WO2011162320A1 | 2011-12-29 | |||
| WO2015199169A1 | 2015-12-30 |
Foreign References:
| JP2005075790A | 2005-03-24 | |||
| JP2007119412A | 2007-05-17 | |||
| JP2005336117A | 2005-12-08 | |||
| JP2001039881A | 2001-02-13 | |||
| JPH083054A | 1996-01-09 | |||
| JPH1077231A | 1998-03-24 | |||
| JP2017151708A | 2017-08-31 |
Other References:
YOSHIMOTO, TAKANORI: "Oolonghomobisflavan B induces apoptosis in multiple myeloma cells via 67LR", JSOFF LETTER, vol. 71, 15 June 2017 (2017-06-15), pages 1 - 16, XP055673452
KUMAZOE, M.: "67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 123, no. 2, February 2013 (2013-02-01), pages 787 - 799, XP055483787
NAKAMURA, JUNICHI ET AL.: "Lowering effects on visceral fat of the OTPP (Oolong Tea Polymerized Polyphenols) enriched oolong tea (FOSHU ''KURO- Oolong Tea OTPP'') in over weight volunteers)", JAPANESE PHARMACOLOGY & THERAPEUTICS, vol. 35, no. 6, June 2007 (2007-06-01), pages 661 - 671, XP009519209
MATSUI, YOKICHI: "The attructive power of Oolong Tea ", JOURNAL FOR THE INTEGRATED STUDY OF DIETARY HABITS, vol. 11, no. 1, 1 January 2000 (2000-01-01), pages 2 - 15, XP055673456
KHAN N ET AL.: "Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate", CANCER RES., vol. 66, no. 5, 2006, pages 2500 - 2505
SHANAFELT TD ET AL.: "Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia", J. CLIN.ONCOL., vol. 27, no. 23, 2009, pages 3808 - 3814
TACHIBANA H ET AL.: "A receptor for green tea polyphenol EGCG", NAT.STRUCT. MOL. BIOL., vol. 11, no. 4, 2004, pages 380 - 381, XP002980515, DOI: 10.1038/nsmb743
See also references of EP 3662906A4
KUMAZOE, M.: "67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 123, no. 2, February 2013 (2013-02-01), pages 787 - 799, XP055483787
NAKAMURA, JUNICHI ET AL.: "Lowering effects on visceral fat of the OTPP (Oolong Tea Polymerized Polyphenols) enriched oolong tea (FOSHU ''KURO- Oolong Tea OTPP'') in over weight volunteers)", JAPANESE PHARMACOLOGY & THERAPEUTICS, vol. 35, no. 6, June 2007 (2007-06-01), pages 661 - 671, XP009519209
MATSUI, YOKICHI: "The attructive power of Oolong Tea ", JOURNAL FOR THE INTEGRATED STUDY OF DIETARY HABITS, vol. 11, no. 1, 1 January 2000 (2000-01-01), pages 2 - 15, XP055673456
KHAN N ET AL.: "Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate", CANCER RES., vol. 66, no. 5, 2006, pages 2500 - 2505
SHANAFELT TD ET AL.: "Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia", J. CLIN.ONCOL., vol. 27, no. 23, 2009, pages 3808 - 3814
TACHIBANA H ET AL.: "A receptor for green tea polyphenol EGCG", NAT.STRUCT. MOL. BIOL., vol. 11, no. 4, 2004, pages 380 - 381, XP002980515, DOI: 10.1038/nsmb743
See also references of EP 3662906A4
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
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