AIRWAY MUCUS SECRETION INHIBITORS - ONO PHARMACEUTICAL CO

Title:

AIRWAY MUCUS SECRETION INHIBITORS

Document Type and Number:

WIPO Patent Application WO/2002/026229

Kind Code:

A1

Abstract:

Remedies and/or preventives for diseases accompanied by the excessive airway mucus secretion which contain 5-membered heterocyclic compounds represented by the following general formula (I) or nontoxic salts thereof as the active ingredient: (I) wherein Z represents an a-aminocarbonyl-containing group; R?1¿ represents (1) substituted alkyl, alkenyl or alkynyl, (2) OH, (3) amino, (4) alkylamino, (5) dialkylamino, etc.; and X and Y represent each O, S or a substituted N atom.

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Inventors:

NAGAI ATSUSHI (JP)
SHIRAJI TAKAMITSU (JP)

Application Number:

PCT/JP2001/008569

Publication Date:

April 04, 2002

Filing Date:

September 28, 2001

Export Citation:

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Assignee:

ONO PHARMACEUTICAL CO (JP)
NAGAI ATSUSHI (JP)
SHIRAJI TAKAMITSU (JP)

International Classes:

A61K31/00; A61K31/4245; A61K31/4355; A61K31/4365; A61K31/437; A61K31/4439; A61K31/47; A61K31/4725; A61K31/513; A61K31/5377; A61K31/55; A61K31/551; A61K31/5513; A61P11/06; C07D413/12; C07D487/06; C07D491/048; C07K5/02; C07K5/08; C07K5/083; C07K5/097; (IPC1-7): A61K31/4245; A61K31/4355; A61K31/4365; A61K31/437; A61K31/4439; A61K31/4725; A61K31/513; A61K31/5377; A61K31/55; A61K38/05; A61P11/06

Domestic Patent References:

WO1998024806A2	1998-06-11
WO1996016080A1	1996-05-30
WO2001044214A1	2001-06-21
WO2001040204A1	2001-06-07
WO2000052032A1	2000-09-08
WO1993018059A2	1993-09-16

Foreign References:

JPH06298663A

1994-10-25

Other References:

CHEMICAL ABSTRACTS, vol. 131, Columbus, Ohio, US; abstract no. 115190, XP002906733
CHEMICAL ABSTRACTS, vol. 124, Columbus, Ohio, US; abstract no. 114174, XP002906732

Attorney, Agent or Firm:

Ohie, Kunihisa (2-6 Nihonbashi-Ningyocho 2-chome Chuo-ku, Tokyo, JP)

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