Title:
AKKERMANSIA MUCINIPHILA EB-AMDK27 STRAIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/040186
Kind Code:
A1
Abstract:
Disclosed are a novel Akkermansia muciniphila EB-AMDK27 strain having the effect of preventing or treating inflammatory disease or metabolic disease, and a pharmaceutical composition effective for preventing or treating inflammatory disease or metabolic disease, which contains the strain, a culture thereof, or a dried product thereof. While traditional probiotics generally have insufficient therapeutic effects on inflammatory or metabolic diseases, the disclosed next-generation probiotic strain has an excellent effect on the prevention or treatment of inflammatory disease and/or metabolic disease so that it may be used as a new prophylactic and therapeutic tool.
Inventors:
SEO JAE-GU (KR)
SHIN JOO-HYUN (KR)
LEE DO-KYUNG (KR)
SHIN JOO-HYUN (KR)
LEE DO-KYUNG (KR)
Application Number:
PCT/KR2020/006176
Publication Date:
March 04, 2021
Filing Date:
May 11, 2020
Export Citation:
Assignee:
ENTEROBIOME INC (KR)
International Classes:
C12N1/20; A23L33/135; A61K35/74; A61P3/00; C12R1/01
Foreign References:
| KR20150093711A | 2015-08-18 | |||
| KR20150133646A | 2015-11-30 | |||
| KR101809172B1 | 2017-12-14 | |||
| KR20130021920A | 2013-03-06 | |||
| KR20110095929A | 2011-08-25 | |||
| KR100996577B1 | 2010-11-24 | |||
| KR20110010015A | 2011-01-31 | |||
| KR20190034796A | 2019-04-03 |
Other References:
DATABASE PROTEIN 11 December 2013 (2013-12-11), "carboxyl-terminal protease [Akkermansia muciniphila ATCC BAA-835]", XP055785809, retrieved from NCBI Database accession no. ACD05451
WRENBLOOM, GASTROENTEROLOGY, vol. 132, 2007, pages 2116 - 2130
JEON T. ET AL.: "Red yeast rice extracts suppress adipogenesis by down-regulating adipogenic transcription factors and gene expression in 3T3-L1", LIFE SCI., vol. 75, no. 26, pages 3195 - 3203, XP004601760, DOI: 10.1016/j.lfs.2004.06.012
See also references of EP 3802787A4
WRENBLOOM, GASTROENTEROLOGY, vol. 132, 2007, pages 2116 - 2130
JEON T. ET AL.: "Red yeast rice extracts suppress adipogenesis by down-regulating adipogenic transcription factors and gene expression in 3T3-L1", LIFE SCI., vol. 75, no. 26, pages 3195 - 3203, XP004601760, DOI: 10.1016/j.lfs.2004.06.012
See also references of EP 3802787A4
Attorney, Agent or Firm:
KIM, Hak Je et al. (KR)
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