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Title:
AKKERMANSIA MUCINIPHILA, USE THEREOF, AND CULTURING METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/237038
Kind Code:
A1
Abstract:
Akkermansia muciniphila strains, which respectively have the preservation numbers CGMCC No. 22793 and CGMCC No. 22794, probiotic combination products comprising said strains, a health food or a pharmaceutical composition, a method for culturing the strains, and an application of the strains in preparation of a health food or a drug for preventing and treating non-alcoholic fatty liver disease. The strains obtained via separation may be used for preventing and treating the occurrence, development, and worsening of non-alcoholic fatty liver disease, can reduce liver fat and hepatitis, improve liver function indicators, reduce mild endotoxemia, and inhibit hepatic fibrosis.

Inventors:
ZHENG LIJUN (CN)
LIU YANGYANG (CN)
WANG WEI (CN)
LIANG DEBAO (CN)
WANG YE (CN)
ZHI FACHAO (CN)
Application Number:
PCT/CN2023/099055
Publication Date:
December 14, 2023
Filing Date:
June 08, 2023
Export Citation:
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Assignee:
GUANGZHOU ZHIYI BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K35/74; A21D2/08; A21D13/06; A23L33/135; A61P1/16; C12N1/20; C12R1/01
Foreign References:
CN114949003A2022-08-30
CN104918626A2015-09-16
CN108289918A2018-07-17
CN113330109A2021-08-31
CN113906129A2022-01-07
CN114514028A2022-05-17
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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