Title:
ALDOL REACTION CATALYST
Document Type and Number:
WIPO Patent Application WO/2014/203944
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an aldol reaction catalyst and a method for producing a stereoselective cyclic β-hydroxy aldehyde compound using this catalyst.
As a means for solving the above-mentioned problem, the present invention provides a biaryl-type aldol reaction catalyst which is represented by general formula (I).
(In the formula, R1, R2, R3a, R4a, Ra and R are as defined in the description.)
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Inventors:
FURUTA TAKUMI (JP)
BABA TOMONORI (JP)
KAWABATA TAKEO (JP)
BABA TOMONORI (JP)
KAWABATA TAKEO (JP)
Application Number:
PCT/JP2014/066205
Publication Date:
December 24, 2014
Filing Date:
June 18, 2014
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
B01J31/02; C07C45/65; C07C47/36; C07B53/00; C07C311/09; C07C311/21; C07D207/48; C07D211/22
Domestic Patent References:
| WO2010047318A1 | 2010-04-29 |
Other References:
T.FURUTA ET AL.: "Synthesis of Axially Chiral Amino Acid Derivatives via the Selective Monoesterification of 1,1'-Biaryl-2,2'- dicarboxylic Acids", SYNTHESIS, vol. 45, no. 10, 17 May 2013 (2013-05-17), pages 1312 - 1318
TAICHI KANO ET AL.: "syn-Selective and Enantioselective Direct Cross-Aldol Reactions between Aldehydes Catalyzed by an Axially Chiral Amino Sulfonamide", ANGEW. CHEM. INT. ED., vol. 46, no. 10, 2007, pages 1738 - 1740
TAICHI KANO ET AL.: "A Designer Axially Chiral Amino Sulfonamide as an Efficient Organocatalyst for Direct Asymmetric anti- Selective Mannich Reactions and syn-Selective Cross-Aldol Reactions", CHEM. EUR. J., vol. 15, no. 27, 2009, pages 6678 - 6687
TOMOAKI BABA ET AL.: "Jikusei Fusei Aniline- gata Amino San Ruientai ni yoru Goinkan Kanka Bunshi-nai Fusei Aldol Hanno no Kaihatsu", THE JAPANESE SOCIETY FOR PROCESS CHEMISTRY SUMMER SYMPOSIUM KOEN YOSHISHU, vol. 2013, 21 June 2013 (2013-06-21), pages 214 - 215
TOMOAKI BABA ET AL.: "Aniline Amino-ki o Motsu San -Enki-gata Jikusei Fusei Shokubai ni yoru Bunshi-nai Kosa Aldol Hanno no Kaihatsu", ABSTRACTS OF ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN, vol. 134, 12 May 2014 (2014-05-12)
TOMOAKI BABA ET AL.: "Aniline Amino-ki o Motsu San -Enki-gata Jikusei Fusei Shokubai ni yoru Bunshi-nai Kosa Aldol Hanno no Kaihatsu", ABSTRACTS OF SYMPOSIUM ON MEDICINAL CHEMISTRY, vol. 31, 1 November 2013 (2013-11-01)
TAICHI KANO ET AL.: "syn-Selective and Enantioselective Direct Cross-Aldol Reactions between Aldehydes Catalyzed by an Axially Chiral Amino Sulfonamide", ANGEW. CHEM. INT. ED., vol. 46, no. 10, 2007, pages 1738 - 1740
TAICHI KANO ET AL.: "A Designer Axially Chiral Amino Sulfonamide as an Efficient Organocatalyst for Direct Asymmetric anti- Selective Mannich Reactions and syn-Selective Cross-Aldol Reactions", CHEM. EUR. J., vol. 15, no. 27, 2009, pages 6678 - 6687
TOMOAKI BABA ET AL.: "Jikusei Fusei Aniline- gata Amino San Ruientai ni yoru Goinkan Kanka Bunshi-nai Fusei Aldol Hanno no Kaihatsu", THE JAPANESE SOCIETY FOR PROCESS CHEMISTRY SUMMER SYMPOSIUM KOEN YOSHISHU, vol. 2013, 21 June 2013 (2013-06-21), pages 214 - 215
TOMOAKI BABA ET AL.: "Aniline Amino-ki o Motsu San -Enki-gata Jikusei Fusei Shokubai ni yoru Bunshi-nai Kosa Aldol Hanno no Kaihatsu", ABSTRACTS OF ANNUAL MEETING OF PHARMACEUTICAL SOCIETY OF JAPAN, vol. 134, 12 May 2014 (2014-05-12)
TOMOAKI BABA ET AL.: "Aniline Amino-ki o Motsu San -Enki-gata Jikusei Fusei Shokubai ni yoru Bunshi-nai Kosa Aldol Hanno no Kaihatsu", ABSTRACTS OF SYMPOSIUM ON MEDICINAL CHEMISTRY, vol. 31, 1 November 2013 (2013-11-01)
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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