Title:
ALKALINE PHOSPHATASE ENZYMATIC CHEMILUMINESCENT SUBSTRATE
Document Type and Number:
WIPO Patent Application WO/2016/206654
Kind Code:
A2
Abstract:
The present invention relates to an alkaline phosphatase enzymatic chemiluminescent substrate. The enzymatic chemiluminescent substrate uses water as a solvent, and also comprises the following components: 2-amino-2-methyl-1-propanol; AMPPD; a luminescence enhancer which is sodium fatty alcohol polyoxyethylene ether carboxylate coupled with a fluorescent compound. The luminescence enhancer has a co-surfactant effect, allowing the complex to be better combined into a chemiluminescent buffer system, thereby significantly increasing the chemiluminescent efficiency. The alkaline phosphatase enzymatic chemiluminescent substrate has advantages such as high strength, high sensitivity, a long duration and good stability, and fully satisfies clinical detection requirements. A main performance indicator of the chemiluminescent substrate reaches a foreign product level, and the costs of the chemiluminescent substrate are significantly reduced.
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Inventors:
QIN FENG (CN)
MA ZHUFENG (CN)
WANG JING (CN)
ZHANG WEI (CN)
LI QINGCHUN (CN)
MA ZHUFENG (CN)
WANG JING (CN)
ZHANG WEI (CN)
LI QINGCHUN (CN)
Application Number:
PCT/CN2016/096755
Publication Date:
December 29, 2016
Filing Date:
August 25, 2016
Export Citation:
Assignee:
SUZHOU HAOOUBO BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
G01N33/53; G01N21/76
Attorney, Agent or Firm:
SUZHOU CREATOR PATENT & TRADEMARK AGENCY LTD. (CN)
苏州创元专利商标事务所有限公司 (CN)
苏州创元专利商标事务所有限公司 (CN)
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