Title:
ALKYLSULFAMOYL INDAZOLE CARBOXAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/192588
Kind Code:
A1
Abstract:
The present invention relates to an alkylsulfamoyl indazole carboxamide derivative, a preparation method therefor, and a pharmaceutical use thereof. In particular, disclosed are a compound of formula (I) or a pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug thereof, a preparation method therefor, and an application thereof. The definition of each group in the formula is detailed in the description.
Inventors:
ZHOU FUSHENG (CN)
XIE JING (CN)
HUANG DONG (CN)
LAN JIONG (CN)
XIE JING (CN)
HUANG DONG (CN)
LAN JIONG (CN)
Application Number:
PCT/CN2020/080450
Publication Date:
October 01, 2020
Filing Date:
March 20, 2020
Export Citation:
Assignee:
SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN)
YANGTZE RIVER PHARM GROUP CO (CN)
YANGTZE RIVER PHARM GROUP CO (CN)
International Classes:
C07D401/04; A61K31/416; A61K31/44; A61K31/4412; A61P9/00; A61P11/00; A61P25/00; C07D231/56
Domestic Patent References:
| WO2012095781A1 | 2012-07-19 | |||
| WO2019019851A1 | 2019-01-31 | |||
| WO2016150971A1 | 2016-09-29 |
Foreign References:
| CN108495851A | 2018-09-04 | |||
| CN108495851A | 2018-09-04 | |||
| CN104869992A | 2015-08-26 | |||
| CN107108517A | 2017-08-29 | |||
| CN106243003A | 2016-12-21 |
Other References:
LUO, G. L. ET AL.: "Discovery of Indole- and Indazole-acylsulfonamides as Potent and Selective Nav1.7 Inhibitors for the Treatment of Pain", JOURNAL OF MEDICINAL CHEMISTRY, vol. 62, no. 2, 24 January 2019 (2019-01-24), XP055640118, ISSN: 0022-226, DOI: 20200513104805Y
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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