Title:
ALPHA PROTEIN KINASE 1 INHIBITORS FOR USE IN TREATING ATHEROSCLEROSIS AND RELATED DISEASES
Document Type and Number:
WIPO Patent Application WO/2023/143603
Kind Code:
A1
Abstract:
Use of a compound of Formula I for treating atherosclerosis and related diseases, disorders and conditions in a subject in need of such treatment, wherein the subject in need of such treatment is a subject carrying one or more genetic mutations in ALPK1.
Inventors:
DANG HUAIXIN (CN)
LIU DANYANG (CN)
XU CONG (CN)
MELVINJR LAWRENCE (CN)
FAN JIEQING (CN)
WEI YUNING (CN)
WEI XIONG (CN)
PAN YANFANG (CN)
LICHENSTEIN HENRI (CN)
XU TIAN (CN)
LIU DANYANG (CN)
XU CONG (CN)
MELVINJR LAWRENCE (CN)
FAN JIEQING (CN)
WEI YUNING (CN)
WEI XIONG (CN)
PAN YANFANG (CN)
LICHENSTEIN HENRI (CN)
XU TIAN (CN)
Application Number:
PCT/CN2023/073808
Publication Date:
August 03, 2023
Filing Date:
January 30, 2023
Export Citation:
Assignee:
SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07D277/46; A61K31/426; A61K31/427; A61P9/10; C07D403/12; C07D417/12; C07D417/14
Domestic Patent References:
| WO2008057862A2 | 2008-05-15 | |||
| WO2020176863A1 | 2020-09-03 | |||
| WO2022222888A1 | 2022-10-27 | |||
| WO2003015778A1 | 2003-02-27 |
Other References:
YAMADA YOSHIJI, MATSUI KOTA, TAKEUCHI ICHIRO, FUJIMAKI TETSUO: "Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study", BIOMEDICAL REPORTS MAY 2014 SPANDIDOS PUBLICATIONS GBR, SPANDIDOS PUBLICATIONS, GREECE, vol. 3, no. 3, 1 May 2015 (2015-05-01), Greece , pages 413 - 419, XP093080209, ISSN: 2049-9434, DOI: 10.3892/br.2015.440
Attorney, Agent or Firm:
WU , FENG & ZHANG (CN)
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