Title:
AMIDE COMPOUND HAVING STING INHIBITORY EFFECT, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/032597
Kind Code:
A1
Abstract:
A compound having a STING inhibitory effect or a pharmaceutically acceptable salt thereof, and a use thereof in the preparation of a drug for treating diseases related to abnormal STING expression. Specifically disclosed are compounds of formula I and formula I' or pharmaceutically acceptable salts thereof.
Inventors:
HE CHUAN (CN)
ZHAI WENQIANG (CN)
ZHAO MENGTING (CN)
LIU DONGZHOU (CN)
ZHAI WENQIANG (CN)
ZHAO MENGTING (CN)
LIU DONGZHOU (CN)
Application Number:
PCT/CN2023/111702
Publication Date:
February 15, 2024
Filing Date:
August 08, 2023
Export Citation:
Assignee:
HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D209/40; A61K31/404; A61K31/415; A61K31/4155; A61K31/416; A61K31/4196; A61K31/44; A61K31/497; A61K31/506; A61P29/00; A61P35/00; C07D213/53; C07D231/40; C07D239/26; C07D241/12; C07D255/02
Domestic Patent References:
| WO2020150417A2 | 2020-07-23 | |||
| WO2021138419A1 | 2021-07-08 | |||
| WO2022015975A1 | 2022-01-20 | |||
| WO2021067805A1 | 2021-04-08 | |||
| WO2021067791A1 | 2021-04-08 |
Foreign References:
| CN112823036A | 2021-05-18 |
Other References:
DATABASE REGISTRY ANONYMOUS : " 4-Morpholineacetamide, N-benzo[b]thien-3-yl-2,2,3-trimethyl-.alpha.-oxo- (CA INDEX NAME)", XP093139888, retrieved from STN
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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