Title:
AMIDE COMPOUND, PHARMACEUTICAL COMPOSITION AND RXR FUNCTION CONTROL AGENT
Document Type and Number:
WIPO Patent Application WO/2005/087713
Kind Code:
A1
Abstract:
Disclosed is an amide compound having high activity as an RXR ligand which is free of side effects. Also disclosed are an RXR function control agent composed of such an amide compound, an RXR/PPAR heterodimer function control agent composed of such an amide compound, and a pharmaceutical composition containing such an amide compound. Specifically disclosed is a compound represented by the general formula (1) below or a salt thereof. (In the formula (1), R1-R4, Ar, V, W and Z are as specifically defined in claims and the description.)
Inventors:
IKESHITA SHINJI (JP)
YAMAMOTO JUNJI (JP)
SHINOHARA MASASHI (JP)
YAMAMOTO JUNJI (JP)
SHINOHARA MASASHI (JP)
Application Number:
PCT/JP2005/004357
Publication Date:
September 22, 2005
Filing Date:
March 11, 2005
Export Citation:
Assignee:
SAKAI CHEMICAL INDUSTRY CO (JP)
IKESHITA SHINJI (JP)
YAMAMOTO JUNJI (JP)
SHINOHARA MASASHI (JP)
IKESHITA SHINJI (JP)
YAMAMOTO JUNJI (JP)
SHINOHARA MASASHI (JP)
International Classes:
A61K31/195; A61K31/44; A61P3/06; A61P3/10; A61P9/10; A61P25/16; A61P25/28; A61P43/00; C07C233/87; (IPC1-7): C07C233/87; A61K31/195; A61K31/44; A61P3/06; A61P3/10; A61P9/10; A61P25/16; A61P25/28; A61P43/00
Foreign References:
| JP2000500499A | 2000-01-18 | |||
| JPH11511472A | 1999-10-05 |
Attorney, Agent or Firm:
Yasutomi, Yasuo (4-20 Nishinakajima 5-chome, Yodogawa-k, Osaka-shi Osaka 11, JP)
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