Title:
AMIDE DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2002/051796
Kind Code:
A1
Abstract:
Amide derivatives represented by the general formula (I), or pharmacologically acceptable salts, esters or other derivatives thereof, exhibiting excellent LDL-antioxidant and ACAT-inhibitory effects: (I) wherein R?1¿ is hydroxyl or lower alkoxy; R?2¿ is lower alkanoyl; R?3¿ is carboxyl, carbamoyl, mono(lower alkyl)carbamoyl, or di(lower alkyl)carbamoyl; and A is a single bond or C¿1-6? alkylene.
Inventors:
KOGEN HIROSHI (JP)
MIYAZAKI ATSUHIRO (JP)
HAYAKAWA ICHIRO (JP)
TAMURA AKIHIRO (JP)
MIYAZAKI ATSUHIRO (JP)
HAYAKAWA ICHIRO (JP)
TAMURA AKIHIRO (JP)
Application Number:
PCT/JP2001/011295
Publication Date:
July 04, 2002
Filing Date:
December 21, 2001
Export Citation:
Assignee:
SANKYO CO (JP)
KOGEN HIROSHI (JP)
MIYAZAKI ATSUHIRO (JP)
HAYAKAWA ICHIRO (JP)
TAMURA AKIHIRO (JP)
KOGEN HIROSHI (JP)
MIYAZAKI ATSUHIRO (JP)
HAYAKAWA ICHIRO (JP)
TAMURA AKIHIRO (JP)
International Classes:
A61P3/06; A61P9/10; A61P43/00; C07C237/22; (IPC1-7): C07C237/22; A61K31/167; A61K31/196; A61P3/06; A61P9/10; A61P43/00; C07C237/42
Foreign References:
| JPH08295667A | 1996-11-12 |
Other References:
CHANG MING RONG ET AL.: "Synthesis of 7-substituted indolo(3,2-b)quinoline derivatives", HETEROCYCLES, vol. 33, no. 1, 1992, pages 147 - 152, XP002950703
Attorney, Agent or Firm:
Ohno, Akio c/o SANKYO COMPANY (LIMITED 2-58 Hiromachi 1-chome Shinagawa-ku, Tokyo, JP)
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