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Title:
α-AMINO-N-SUBSTITUTED AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2008/000131
Kind Code:
A1
Abstract:
The present application discloses a type of α-amino-N-substituted amide compounds, compositions and uses thereof. The present compounds are represented by general formula I. It is easy to prepare these compounds. These compounds have strong anti-cancer activity.

Inventors:
NAN FAJUN (CN)
LI JIA (CN)
DING JIAN (CN)
LIU GANG (CN)
XIE CHUANMING (CN)
CHEN YI (CN)
TAI WANYI (CN)
Application Number:
PCT/CN2007/001470
Publication Date:
January 03, 2008
Filing Date:
April 29, 2007
Export Citation:
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Assignee:
SHANGHAI INST MATERIA MEDICA (CN)
NAN FAJUN (CN)
LI JIA (CN)
DING JIAN (CN)
LIU GANG (CN)
XIE CHUANMING (CN)
CHEN YI (CN)
TAI WANYI (CN)
International Classes:
C07D223/12; A61K31/397; A61K31/40; A61K31/4422; A61K31/55; A61P35/00; C07D205/06; C07D207/02; C07D207/18; C07D211/38; C07D401/06
Domestic Patent References:
WO2006056696A22006-06-01
WO2005014574A12005-02-17
WO2002072555A12002-09-19
Other References:
SARABIA ET AL.: "Total Synthesis of Bengamide E and Analogues by Modification at C-2 and at Terminal Olefinic Positions", J. ORG. CHEM., vol. 70, no. 23, 19 September 2002 (2002-09-19), pages 9514 - 9520
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (Block B KingSound International Center,116 Zizhuyuan Road,Haidian District, Beijing 7, CN)
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