AMINOPYRAZOLE DERIVATIVES - CHUGAI PHARMACEUTICAL CO LTD

Title:

AMINOPYRAZOLE DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/2016/204261

Kind Code:

A1

Abstract:

The present invention addresses the problem of providing low-molecular compounds capable of inhibiting Src family kinases. The present invention pertains to a compound represented by general formula (I) or pharmacologically acceptable salts thereof. In the formula, Ar1 is an optionally substituted C6-10 arylene or five- to ten-membered heteroarylene, and Ar2 is an optionally substituted C6-10 aryl or five- to ten-membered heteroaryl. R1 and R2 mean the same as defined in the specification.

Inventors:

EBIIKE HIROSATO (JP)
AOKI TOSHIHIRO (JP)
CHIBA TAKASHI (JP)
KOCHI MASAMI (JP)
NAKAMA KIMITAKA (JP)
NIIZUMA SATOSHI (JP)
NISHII HIROKI (JP)
OHWADA JUN (JP)
SHIMAMURA HIROYUKI (JP)
SUGE AIKO (JP)
NAKANISHI YOSHITO (JP)
KOBAYASHI NATSUKI (JP)

Application Number:

PCT/JP2016/068039

Publication Date:

December 22, 2016

Filing Date:

June 17, 2016

Export Citation:

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Assignee:

CHUGAI PHARMACEUTICAL CO LTD (JP)
HOFFMANN LA ROCHE (CH)

International Classes:

C07D401/14; A61K31/4155; A61K31/4178; A61K31/4188; A61K31/422; A61K31/427; A61K31/433; A61K31/438; A61K31/4439; A61K31/454; A61K31/4545; A61K31/496; A61K31/4995; A61K31/506; A61K31/5377; A61P1/00; A61P1/16; A61P11/00; A61P35/00; A61P43/00; C07D403/06; C07D403/14; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D471/10; C07D487/04; C07D487/08; C07D487/10; C07D491/107; C07D498/08; C07D513/10

Domestic Patent References:

WO2011016528A1	2011-02-10
WO2014051022A1	2014-04-03
WO2015016295A1	2015-02-05
WO2015086636A1	2015-06-18
WO2015086635A1	2015-06-18
WO2015086642A1	2015-06-18

Foreign References:

JP2012180344A

2012-09-20

Other References: