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Title:
Ammoniumsalze und Ammoniumsalz-MineralsalzclathratAmmonium salts and ammonium salt/mineral salt clate als transport-und wirkform f}r pharmazeutisch-mehrate compounds for use as vehicle and effective form for pharmaco-medical applications and for use dizinische und als Phasentransfermittel f}r chemische Anwendungen as phase transfer agents for chemical applications
Document Type and Number:
WIPO Patent Application WO2006007835
Kind Code:
A8
Abstract:
The invention relates to ammonium salts and stable storable ammonium salt/mineral salt clathrate compounds (inclusion compounds) having acidic dibasic acid residues such as hydrocarbonate, to methods for producing them and to pharmaco-medical and chemical synthetic applications for said compounds. According to the invention, compounds for pharmaco-medical and chemical synthetic applications are produced which comprise the ammonium salt and ammonium/mineral salt clathrate compounds (inclusion compounds, clusters) having acidic dibasic anionic acid residues of general formula (I) * x mole mineral salt, wherein R1, R2, R3 and R4 = alkyl and substituted alkyl straight-chain or branched, optionally having an alcohol, ether, silylether, ester, amino or amide function, H or aryl-alkyl, whereby aryl is an aromatic or heteroaromatic ring having optionally additional substituents, such as alkyl having 1 to 4 C atoms, OH, NR*2 with R*2= 0, alkyl with alkyl of from 1 to 4 C atoms or H, COOH, COOR, CN, NO2 and the cationic positive N+ optionally is part of an active agent, Y = a dibasic acid residue of an organic dicarboxylic acid or CO3, corresponding to HY- = HCO3

Inventors:
KASCH HELMUT (DE)
REUTER UWE (DE)
OETTMEIER RALF (DE)
Application Number:
PCT/DE2005/001288
Publication Date:
June 29, 2006
Filing Date:
July 20, 2005
Export Citation:
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Assignee:
KASCH HELMUT (DE)
REUTER UWE (DE)
OETTMEIER RALF (DE)
International Classes:
C07C211/63
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