AMORPHOUS SOLID DISPERSION FORMULATION - TAIGEN BIOTECHNOLOGY CO LTD

Title:

AMORPHOUS SOLID DISPERSION FORMULATION

Document Type and Number:

WIPO Patent Application WO/2022/143844

Kind Code:

A1

Abstract:

Provided is an amorphous solid dispersion containing a Cap-dependent endonuclease inhibitor or a pharmaceutically acceptable salt thereof for oral administration, wherein the Cap-dependent endonuclease inhibitor or a pharmaceutically acceptable salt thereof is dispersed in a matrix formed from the pharmaceutically acceptable polymer. Further disclosed are methods for preparing a above amorphous solid dispersion and a use thereof for treating virus infection and a pharmaceutical composition containing same.

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Inventors:

YEN CHI-FENG (CN)
TIEN FANG-WEI (CN)

Application Number:

PCT/CN2021/142759

Publication Date:

July 07, 2022

Filing Date:

December 30, 2021

Export Citation:

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Assignee:

TAIGEN BIOTECHNOLOGY CO LTD (CN)
TAIGEN BIOPHARMACEUTICALS CO BEIJING LTD (CN)

International Classes:

A61K31/5025; A61K9/10; A61K9/14; A61K31/503; A61P31/16; C07D471/04

Domestic Patent References:

WO2019144089A1	2019-07-25
WO2019220352A1	2019-11-21
WO2020015669A1	2020-01-23

Foreign References:

CN111253391A	2020-06-09
CA2871886A1	2015-05-19
CN111217810A	2020-06-02

Attorney, Agent or Firm:

GE CHENG & CO., LTD (CN)

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