Title:
ANALYSIS METHOD FOR PEPTIDE BOUND TO CARRIER FOR LIQUID PHASE PEPTIDE SYNTHESIS
Document Type and Number:
WIPO Patent Application WO/2023/277186
Kind Code:
A1
Abstract:
Provided is a means that makes it possible to simultaneously and accurately analyze a target peptide, a component derived from a carrier for liquid phase peptide synthesis, and the like. Provided is a method for simultaneously analyzing a carrier for liquid phase peptide synthesis, a component derived from the carrier for liquid phase peptide synthesis, an amino acid to which the carrier for liquid phase peptide synthesis is bound, a peptide compound to which the carrier for liquid phase peptide synthesis is bound, and a target peptide or a final target peptide, said method being characterized in that supercritical fluid chromatography or high performance liquid chromatography using an alcohol as an eluent is used.
Inventors:
NEMOTO YOSHITAKA (JP)
ABE HITOSHI (JP)
MORI TOSHIHIRO (JP)
ABE HITOSHI (JP)
MORI TOSHIHIRO (JP)
Application Number:
PCT/JP2022/026477
Publication Date:
January 05, 2023
Filing Date:
July 01, 2022
Export Citation:
Assignee:
PEPTISTAR INC (JP)
SEKISUI MEDICAL CO LTD (JP)
SEKISUI MEDICAL CO LTD (JP)
International Classes:
C07K1/04; B01D15/32; B01D15/40; B01D15/42; C07K1/16; C07K2/00; G01N30/02; G01N30/26; G01N30/88
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Other References:
TSUDA SHUGO, MASAYOSHI MOCHIZUKI, HIROYUKI ISHIBA , KUMIKO YOSHIZAWA-KUMAGAYE, HIDEKI NISHIO, SHINYA OISHI, TAKU YOSHIYA : "Easy-to-Attach/Detach Solubilizing-Tag-Aided Chemical Synthesis of an Aggregative Capsid Protein", ANGEW. CHEM. INT. ED., vol. 57, no. 8, 25 January 2018 (2018-01-25), pages 2105 - 2109, XP093019246, DOI: 10.1002/anie.201711546
YANO SHINYA, MORI TOSHIHIRO, KUBOTA HIDEKI: "Silylated Tag-Assisted Peptide Synthesis: Continuous One-Pot Elongation for the Production of Difficult Peptides under Environmentally Friendly Conditions", MOLECULES, vol. 26, no. 12, pages 3497, XP093019249, DOI: 10.3390/molecules26123497
ANGEW CHEM INT ED ENGL., vol. 56, 2017, pages 7803 - 7807
ANGEW CHEM INT ED ENGL., vol. 60, 2021, pages 7786 - 7795
ANGEW CHEM INT ED ENGL., vol. 57, 2018, pages 2105 - 2109
YANO SHINYA, MORI TOSHIHIRO, KUBOTA HIDEKI: "Silylated Tag-Assisted Peptide Synthesis: Continuous One-Pot Elongation for the Production of Difficult Peptides under Environmentally Friendly Conditions", MOLECULES, vol. 26, no. 12, pages 3497, XP093019249, DOI: 10.3390/molecules26123497
ANGEW CHEM INT ED ENGL., vol. 56, 2017, pages 7803 - 7807
ANGEW CHEM INT ED ENGL., vol. 60, 2021, pages 7786 - 7795
ANGEW CHEM INT ED ENGL., vol. 57, 2018, pages 2105 - 2109
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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