Title:
ANALYSIS OF POLYNUCLEOTIDES
Document Type and Number:
WIPO Patent Application WO/2014/200926
Kind Code:
A3
Abstract:
According to some embodiments herein, methods and kits for labeling and analyzing nucleic acids are provided, In some embodiments, sequence-specific labeling is performed on polynucleotide sequences associated with a host genome, and the presence or absence of patterns characteristic of extragenomic sequences are determined.
Inventors:
CAO HAN (US)
HASTIE ALEX R (US)
LAM ERNEST TSZ-TSUN (US)
HASTIE ALEX R (US)
LAM ERNEST TSZ-TSUN (US)
Application Number:
PCT/US2014/041568
Publication Date:
March 12, 2015
Filing Date:
June 09, 2014
Export Citation:
Assignee:
BIONANO GENOMICS INC (US)
International Classes:
C12Q1/68; C07H21/00; C07H21/02; G16B30/10
Other References:
LAM ET AL.: "Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly.", NAT BIOTECHNOL, vol. 30, no. 8, August 2012 (2012-08-01), pages 771 - 776, XP002739644
BADAY ET AL.: "Multicolor super-resolution DNA imaging for genetic analysis.", NANO LETT, vol. 12, no. 7, 11 June 2012 (2012-06-11), pages 3861 - 3866, XP055268597
DAS ET AL., SINGLE MOLECULE LINEAR ANALYSIS OF DNA IN NANO-CHANNEL LABELED WITH SEQUENCE SPECIFIC FLUORESCENT PROBES., vol. 38, no. 18, October 2012 (2012-10-01), pages E177 1 - 8, XP002670980
BEN-DAVID ET AL.: "Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus.", PROC NAT ACAD SCI, vol. 87, no. 4, February 1990 (1990-02-01), pages 1332 - 1336, XP055300966
BADAY ET AL.: "Multicolor super-resolution DNA imaging for genetic analysis.", NANO LETT, vol. 12, no. 7, 11 June 2012 (2012-06-11), pages 3861 - 3866, XP055268597
DAS ET AL., SINGLE MOLECULE LINEAR ANALYSIS OF DNA IN NANO-CHANNEL LABELED WITH SEQUENCE SPECIFIC FLUORESCENT PROBES., vol. 38, no. 18, October 2012 (2012-10-01), pages E177 1 - 8, XP002670980
BEN-DAVID ET AL.: "Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus.", PROC NAT ACAD SCI, vol. 87, no. 4, February 1990 (1990-02-01), pages 1332 - 1336, XP055300966
Attorney, Agent or Firm:
MILLER, Kimberly, J. (2040 Main Street14th FLOO, Irvine CA, US)
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