Title:
ANTI-ADIPONECTIN RECEPTOR ANTIBODY AND UTILIZATION OF SAME
Document Type and Number:
WIPO Patent Application WO/2024/096022
Kind Code:
A1
Abstract:
Provided is an anti-adiponectin antibody or an antibody fragment thereof in which LCDR1 includes an amino acid sequence of SEQ ID NO: 17 or 18, LCDR2 includes an amino acid sequence of SEQ ID NO: 19 or 20, LCDR3 includes an amino acid sequence of SEQ ID NO: 21, HCDR1 includes an amino acid sequence of SEQ ID NO: 22, HCDR2 includes an amino acid sequence of SEQ ID NO: 23, and HCDR3 includes an amino acid sequence of SEQ ID NO: 24.
Inventors:
ASAHARA NAOMI (JP)
WADA KOICHI (JP)
YAMAUCHI TOSHIMASA (JP)
IWABU MIKI (JP)
KADOWAKI TAKASHI (JP)
IWABU MASATO (JP)
WADA KOICHI (JP)
YAMAUCHI TOSHIMASA (JP)
IWABU MIKI (JP)
KADOWAKI TAKASHI (JP)
IWABU MASATO (JP)
Application Number:
PCT/JP2023/039323
Publication Date:
May 10, 2024
Filing Date:
October 31, 2023
Export Citation:
Assignee:
MITSUBISHI TANABE PHARMA CORP (JP)
UNIV TOKYO (JP)
UNIV TOKYO (JP)
International Classes:
C12N15/13; A61K39/395; A61P3/06; A61P3/10; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63
Domestic Patent References:
| WO2017086419A1 | 2017-05-26 |
Foreign References:
| US20220249458A1 | 2022-08-11 |
Other References:
JUNG DOKYUNG; BUCHER FELICITAS; RYU SUYEON; JEONG JONGWON; LEE BEOM YONG; JEONG YOUNGTAE; KIM MINSEOK S.; OH YONG-SEOK; BAEK MOON-: "An adiponectin receptor agonist antibody stimulates glucose uptake and fatty-acid oxidation by activating AMP-activated protein kinase", CYTOKINE, ACADEMIC PRESS LTD, PHILADELPHIA, PA, US, vol. 126, 16 October 2019 (2019-10-16), US , XP085973005, ISSN: 1043-4666, DOI: 10.1016/j.cyto.2019.154863
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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