Title:
ANTI-ADRENOMEDULIN NON-NEUTRALIZING ANTIBODY, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/017331
Kind Code:
A1
Abstract:
The present invention belongs to the fields of bioengineering and biological treatment. Disclosed are an anti-ADM monoclonal antibody or a fragment thereof and a pharmaceutical composition, a detection reagent, or a kit comprising the monoclonal antibody or the fragment thereof. Further disclosed is use of the monoclonal antibody or the fragment thereof in the preparation of a drug.
Inventors:
ZHENG YUNCHENG (CN)
DENG SUJUN (CN)
YANG XINXIU (CN)
WANG ZONGDA (CN)
GU CHUNYIN (CN)
DENG SUJUN (CN)
YANG XINXIU (CN)
WANG ZONGDA (CN)
GU CHUNYIN (CN)
Application Number:
PCT/CN2023/108389
Publication Date:
January 25, 2024
Filing Date:
July 20, 2023
Export Citation:
Assignee:
SHANGHAI JEMINCARE PHARMACEUTICAL CO LTD (CN)
International Classes:
C07K16/26; A61K39/395; A61P1/16; A61P3/10; A61P7/10; A61P9/04; A61P9/10; A61P13/12; A61P17/02; A61P31/00; A61P35/00; A61P39/02; C12N5/10; C12N15/13; C12N15/63
Foreign References:
| CN110054690A | 2019-07-26 | |||
| CN114044824A | 2022-02-15 | |||
| CN111511390A | 2020-08-07 | |||
| US20140314775A1 | 2014-10-23 | |||
| EP3339324A1 | 2018-06-27 |
Other References:
XUE GUANG LIU, ZHANG XIU RONG, ZHAO ZHONG HUA, ZHANG ZHI GANG, CHEN QI, GUO MU-YI : "Preparation of Monoclonal Antibody Against Adrenomedullin and Distribution in Human Organ and Tissues", JOURNAL OF SHANGHAI MEDICA(UNIVERSITY), vol. 29, no. 3, 15 May 2002 (2002-05-15), pages 173 - 175, XP093131219
CHRISTOPHER GEVEN ET AL.: "Vascular Effects of Adrenomedullin and the Anti-Adrenomedullin Antibody Adrecizumab in Sepsis", SHOCK., vol. 50, no. 2, 31 August 2018 (2018-08-31), XP055700172, DOI: 10.1097/SHK.0000000000001103
CHRISTOPHER GEVEN ET AL.: "Vascular Effects of Adrenomedullin and the Anti-Adrenomedullin Antibody Adrecizumab in Sepsis", SHOCK., vol. 50, no. 2, 31 August 2018 (2018-08-31), XP055700172, DOI: 10.1097/SHK.0000000000001103
Attorney, Agent or Firm:
BEIJING ORIGINTELLIGENCE IP LAW FIRM (CN)
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