Title:
ANTI-AGEING COSMETIC CARE COMPOSITION COMPRISING CAULERPIN
Document Type and Number:
WIPO Patent Application WO/2024/008902
Kind Code:
A1
Abstract:
The present invention relates to a cosmetic composition for anti-ageing care of the skin, comprising caulerpin in a physiologically acceptable medium. The caulerpin is preferably obtained from Caulerpa racemosa. The invention also relates to a non-therapeutic method for anti-ageing care of a region of the skin, comprising a step of topical application of the composition according to the invention. Finally, according to another aspect, the invention also relates to a method for extracting and purifying caulerpin.
Inventors:
SCHMID RUPERT (FR)
DELAPALME PIERRE-LOUIS (FR)
BOUSCHARAIN LAURE (FR)
DELAPALME PIERRE-LOUIS (FR)
BOUSCHARAIN LAURE (FR)
Application Number:
PCT/EP2023/068799
Publication Date:
January 11, 2024
Filing Date:
July 06, 2023
Export Citation:
Assignee:
B R BIOLOGIQUE RECH (FR)
International Classes:
A61K8/49; A61K8/9722; A61Q19/08
Foreign References:
| BRPI1009162A2 | 2015-08-18 | |||
| JP2004010558A | 2004-01-15 | |||
| ITMI20101406A1 | 2012-01-29 | |||
| JP2004149454A | 2004-05-27 | |||
| JP2017128540A | 2017-07-27 |
Other References:
MENEZES EDUARDA SOARES ET AL: "ANÁLISE TEMPORAL DE FOCOS DE CALOR NA RESERVA DA BIOSFERA DA SERRA DO ESPINHAÇO", 30 April 2019 (2019-04-30), pages 861 - 867, XP093026295, Retrieved from the Internet [retrieved on 20230222], DOI: 10.1590/S0102-
CANTARINO SARAH J. ET AL: "Microwave irradiation is a suitable method for caulerpin extraction from the green algae Caulerpa racemosa (Chlorophyta, Caulerpaceae)", NATURAL PRODUCT RESEARCH, vol. 36, no. 8, 23 November 2020 (2020-11-23), GB, pages 2149 - 2153, XP093026419, ISSN: 1478-6419, DOI: 10.1080/14786419.2020.1844684
L. CAVASY. BASKINK. YURDAKOCN. OLGUN: "Antiproliferative and newly at-tributed apoptotic activities from an invasive marine alga: Caulerpa racemosa var. cylindracea", JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY, vol. 339, 2006, pages 111 - 119
M. VERLAQUEC. DURANDJ.M. HUISMANC-F. BOUDOURESQUEY. LE PARCO: "On the Identity and origin of the Mediterranean invasive Caulerpa racemosa (Caulerpales, Chlorophyta", EUROPEAN JOURNAL OF PHYCOLOGY, vol. 38, no. 4, 2003, pages 325 - 339
D. PESANDOR. LEMÉEC. FERMAP. AMADEJ-P. GIRARD: "Effects of cau-lerpenyne, the major toxin from Caulerpa taxifolia on mechanisms related to sea urchin egg cleavage", AQUATIC TOXICOLOGY, vol. 35, 1996, pages 139 - 155
JOURNAL OF NATURAL PRODUCT, vol. 55, 1992, pages 496 - 499
J.C. ROSSI: "Caulerpin, caulerpicin, Caulerpa scalpellliformis : comparative acute toxicity study", BOTANICA MARINA, vol. 27, 1984, pages 533 - 537
N.S. SARMA, M.S.R. KRISHNA, SK.G. PASHA: "Marine Algal natural products: Contributions from India in the global context", INDIAN JOURNAL OF CHEMISTRY B, vol. 45, 2006, pages 433 - 449
N.R.P.V. MACEDOM.S. RIBEIROR.C. VILLAÇAW. FERREIRAA.M. PINTOV.L. TEIXEIRAC. CIRNE-SANTOSI.C.N.P. PAIXÂOV. GIONGO: "Caulerpin as a potential antiviral drug against herpes simplex virus type 1", BRASILIAN JOURNAL OF PHARMACOGNOSY, vol. 22, no. 4, 2012, pages 861 - 867, XP018504520, DOI: 10.1590/S0102-695X2012005000072
L.H. CAVALCANTE-SILVAA.C. DE CARVALHO CORREJAJ.M. BARBOSA-FILHOB.A. DA SILVAB.V. DE OLIVEIRA SANTOSD.P. DE LIRAS.C. SOUSAG.E. DE M: "Spasmolytic effect of caulerpine involves blockade of Ca2+ influx on guinea pig ileum", MARINE DRUGS, vol. 11, 2013, pages 1553 - 1564
C.S. VAIRAPPAN: "Antibacterial activity of major secondary metabolites: found in for species of edible green macroalgae genus Caulerpa, Asian Journal of Microbiology", BIOTECHNOLOGY AND ENVIRONMENTAL SCIENCES, vol. 6, 2004, pages 197 - 201
A.S.R. ANJANEYULUC.V.S. PRAKASHU.V. MALLAVADHANI: "Two caulerpin analogues and a sequiterpene from Caulerpa racemosa", PHYTOCHEMISTRY, vol. 30, no. 9, 1991, pages 3041 - 3042, XP026631811, DOI: 10.1016/S0031-9422(00)98248-7
E.T.DE SOUZAD.P. DE LIRAA.C. DE QUEIROZD.J.C. DA SILVAA.B. DE AQUINOE.A.C. MELLAV.P. LORENZOG.E.C. DE MIRANDAJ.X. DE ARAÛJO-JÛNIOR: "The antinociceptive and anti-inflammatory activities of caulerpine, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa", MARINE DRUGS, vol. 7, 2009, pages 689 - 704, XP009143582, DOI: 10.3390/md7040689
V.L. TEIXEIRA: "Potential cytotoxic activity of some Brazilian Seaweeds on Human Melanoma Cells", PHYTOTHERAPY RESEARCH, vol. 21, 2007, pages 170 - 175
M.F. RAUBJ.H. CARDELLINAJ.G. SCHWEDE: "The green algal pigment caulerpine as a plant growth regulato", PHYTOCHEMISTRY, vol. 26, 1987, pages 619 - 620
T. NAGAPPANC.S. VAIRAPPAN: "Nutritional and bioactive properties of three edible species of green algae, genus Caulerpa (Caulerpaceae", J. APPL. PHYCOL., vol. 26, 2014, pages 1019 - 1027
N. MOVAHHEDIN, J. BARAN, F.F. AZAD, A. BARZEGARI, H. NAZEMIGEH: "Phytochemistry and biologie activities of Caulerpa pellata native to Oman Sea,", IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, vol. 13, no. 2, 2014, pages 515 - 521
E.L. LEITEH.A.O. ROCHA: "Biological activities of sulfated polysaccharides from tropical seaweeds", BIOMEDICINE AND PHARMACOTHERAPY, vol. 64, 2010, pages 21 - 28, XP026822685
CANTARINO SARAH J. ET AL: "Microwave irradiation is a suitable method for caulerpin extraction from the green algae Caulerpa racemosa (Chlorophyta, Caulerpaceae)", NATURAL PRODUCT RESEARCH, vol. 36, no. 8, 23 November 2020 (2020-11-23), GB, pages 2149 - 2153, XP093026419, ISSN: 1478-6419, DOI: 10.1080/14786419.2020.1844684
L. CAVASY. BASKINK. YURDAKOCN. OLGUN: "Antiproliferative and newly at-tributed apoptotic activities from an invasive marine alga: Caulerpa racemosa var. cylindracea", JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY, vol. 339, 2006, pages 111 - 119
M. VERLAQUEC. DURANDJ.M. HUISMANC-F. BOUDOURESQUEY. LE PARCO: "On the Identity and origin of the Mediterranean invasive Caulerpa racemosa (Caulerpales, Chlorophyta", EUROPEAN JOURNAL OF PHYCOLOGY, vol. 38, no. 4, 2003, pages 325 - 339
D. PESANDOR. LEMÉEC. FERMAP. AMADEJ-P. GIRARD: "Effects of cau-lerpenyne, the major toxin from Caulerpa taxifolia on mechanisms related to sea urchin egg cleavage", AQUATIC TOXICOLOGY, vol. 35, 1996, pages 139 - 155
JOURNAL OF NATURAL PRODUCT, vol. 55, 1992, pages 496 - 499
J.C. ROSSI: "Caulerpin, caulerpicin, Caulerpa scalpellliformis : comparative acute toxicity study", BOTANICA MARINA, vol. 27, 1984, pages 533 - 537
N.S. SARMA, M.S.R. KRISHNA, SK.G. PASHA: "Marine Algal natural products: Contributions from India in the global context", INDIAN JOURNAL OF CHEMISTRY B, vol. 45, 2006, pages 433 - 449
N.R.P.V. MACEDOM.S. RIBEIROR.C. VILLAÇAW. FERREIRAA.M. PINTOV.L. TEIXEIRAC. CIRNE-SANTOSI.C.N.P. PAIXÂOV. GIONGO: "Caulerpin as a potential antiviral drug against herpes simplex virus type 1", BRASILIAN JOURNAL OF PHARMACOGNOSY, vol. 22, no. 4, 2012, pages 861 - 867, XP018504520, DOI: 10.1590/S0102-695X2012005000072
L.H. CAVALCANTE-SILVAA.C. DE CARVALHO CORREJAJ.M. BARBOSA-FILHOB.A. DA SILVAB.V. DE OLIVEIRA SANTOSD.P. DE LIRAS.C. SOUSAG.E. DE M: "Spasmolytic effect of caulerpine involves blockade of Ca2+ influx on guinea pig ileum", MARINE DRUGS, vol. 11, 2013, pages 1553 - 1564
C.S. VAIRAPPAN: "Antibacterial activity of major secondary metabolites: found in for species of edible green macroalgae genus Caulerpa, Asian Journal of Microbiology", BIOTECHNOLOGY AND ENVIRONMENTAL SCIENCES, vol. 6, 2004, pages 197 - 201
A.S.R. ANJANEYULUC.V.S. PRAKASHU.V. MALLAVADHANI: "Two caulerpin analogues and a sequiterpene from Caulerpa racemosa", PHYTOCHEMISTRY, vol. 30, no. 9, 1991, pages 3041 - 3042, XP026631811, DOI: 10.1016/S0031-9422(00)98248-7
E.T.DE SOUZAD.P. DE LIRAA.C. DE QUEIROZD.J.C. DA SILVAA.B. DE AQUINOE.A.C. MELLAV.P. LORENZOG.E.C. DE MIRANDAJ.X. DE ARAÛJO-JÛNIOR: "The antinociceptive and anti-inflammatory activities of caulerpine, a bisindole alkaloid isolated from seaweeds of the genus Caulerpa", MARINE DRUGS, vol. 7, 2009, pages 689 - 704, XP009143582, DOI: 10.3390/md7040689
V.L. TEIXEIRA: "Potential cytotoxic activity of some Brazilian Seaweeds on Human Melanoma Cells", PHYTOTHERAPY RESEARCH, vol. 21, 2007, pages 170 - 175
M.F. RAUBJ.H. CARDELLINAJ.G. SCHWEDE: "The green algal pigment caulerpine as a plant growth regulato", PHYTOCHEMISTRY, vol. 26, 1987, pages 619 - 620
T. NAGAPPANC.S. VAIRAPPAN: "Nutritional and bioactive properties of three edible species of green algae, genus Caulerpa (Caulerpaceae", J. APPL. PHYCOL., vol. 26, 2014, pages 1019 - 1027
N. MOVAHHEDIN, J. BARAN, F.F. AZAD, A. BARZEGARI, H. NAZEMIGEH: "Phytochemistry and biologie activities of Caulerpa pellata native to Oman Sea,", IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, vol. 13, no. 2, 2014, pages 515 - 521
E.L. LEITEH.A.O. ROCHA: "Biological activities of sulfated polysaccharides from tropical seaweeds", BIOMEDICINE AND PHARMACOTHERAPY, vol. 64, 2010, pages 21 - 28, XP026822685
Attorney, Agent or Firm:
TOUROUDE & ASSOCIATES (FR)
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