ANTI-ALPHA-SYNUCLEIN ANTIBODIES AND USES THEREOF

WIPO Patent Application WO/2020/123330

A3

The present invention relates to anti-alpha-synuclein antibodies, and uses thereof for treating diseases such as Parkinsons disease.

WO/1995/029909	NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS
JP2011021022	NEW COMPOUND FOR MODULATING KCNQ CHANNEL AND THEIR PHARMACEUTICAL USE
WO/2001/036423	SPIRO(2H-1-BENZOPYRAN-2,4'-PIPERIDINE) DERIVATES AS GLYCINE TRANSPORT INHIBITORS

CROY JOHNNY EUGENE (US)
HAYASHI MANSUO LU (US)
LU JIRONG (US)
MA BO (US)
TANG YING (US)

PCT/US2019/065134

July 23, 2020

December 09, 2019

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LILLY CO ELI (US)

A61P25/16; A61P25/28; C07K16/18; A61K39/00

WO2017009312A1	2017-01-19
WO2015155694A1	2015-10-15
WO2016061389A2	2016-04-21
WO2013063516A1	2013-05-02
WO2012177972A1	2012-12-27
WO2011104696A1	2011-09-01
WO2017207739A1	2017-12-07
WO2018151821A1	2018-08-23

D. GAMES ET AL: "Reducing C-Terminal-Truncated Alpha-Synuclein by Immunotherapy Attenuates Neurodegeneration and Propagation in Parkinson's Disease-Like Models", THE JOURNAL OF NEUROSCIENCE, vol. 34, no. 28, 9 July 2014 (2014-07-09), US, pages 9441 - 9454, XP055322627, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.5314-13.2014
WINKLER K ET AL: "Changing the antigen binding specificity by single point mutations of an anti-p24 (HIV-1) antibody", THE JOURNAL OF IMMUNOLOGY, AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, vol. 165, no. 8, 15 October 2000 (2000-10-15), pages 4505 - 4514, XP002579393, ISSN: 0022-1767

MCBRIDE, Scott et al. (US)

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