ANTI-B7-H3 ANTIBODY AND PREPARATION THEREFOR AND USE THEREOF

Title:

ANTI-B7-H3 ANTIBODY AND PREPARATION THEREFOR AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/244590

Kind Code:

A1

Abstract:

Provided are an anti-B7-H3 antibody and preparation therefor and a use thereof. Further provided is a drug conjugate and recombinant protein containing the antibody. The antibody of the present invention can be effectively endocytosed by cells, and an antibody-conjugated drug prepared by using the antibody of the present invention shows a tumor inhibition effect.

More Like This:

JP2021524446	Neoadjuvant cancer treatment with a combination of immunotoxins and checkpoint inhibitors
JP2022501377	A novel bispecific antibody for use in the treatment of hematological malignancies
WO/2021/003428	IMMUNOTHERAPY TARGETING CELL SURFACE MARKER CD72 FOR THE TREATMENT OF B-CELL MALIGNANCIES

Inventors:

ZHU LIYUAN (CN)
WANG WENYI (CN)
LANG GUOJUN (CN)
DENG MIN (CN)

Application Number:

PCT/CN2021/098018

Publication Date:

December 09, 2021

Filing Date:

June 02, 2021

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MINGHUI PHARMACEUTICAL SHANGHAI LTD (CN)
MINGHUI PHARMACEUTICAL HANGZHOU LTD (CN)

International Classes:

C07K16/28; A61K39/395; A61K47/68; A61P35/00

Domestic Patent References:

WO2015181267A1	2015-12-03
WO2018161872A1	2018-09-13

Foreign References:

CN110305213A	2019-10-08
CN110950953A	2020-04-03
CN103687945A	2014-03-26
US4816567A	1989-03-28
US4816397A	1989-03-28
US5585089A	1996-12-17

Other References:

MUNSON ET AL., ANAL. BIOCHEM., vol. 107, 1980, pages 220
SAMBROOK ET AL.: "Molecule Clone: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS

Attorney, Agent or Firm:

XU&PARTNERS, LLC. (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: SMART KEY, AND RELAY ATTACK PREVENTION METHOD AND SYSTEM

Next Patent: DRIVING AUXILIARY DEVICE AND METHOD, AND VEHICLE AND STORAGE MEDIUM