Title:
AN ANTI-B7-H3 ANTIBODY
Document Type and Number:
WIPO Patent Application WO/2020/103100
Kind Code:
A1
Abstract:
The present invention provides to antibodies and their immunoreactive fragments binding to an extracellular domain of B7H3 (B7-H3) molecule and the uses thereof, particularly in the treatment of cancers. The invention particularly concerns humanized anti-B7-H3 antibodies and their antigen binding fragments capable of enhancing the activation of the immune system against cancerous cells.
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Inventors:
GUO LI (CN)
DOU YUAN (CN)
SUN TIANTIAN (CN)
LI JIAMING (CN)
QI XIAOQU (CN)
DONG CHEN (CN)
DOU YUAN (CN)
SUN TIANTIAN (CN)
LI JIAMING (CN)
QI XIAOQU (CN)
DONG CHEN (CN)
Application Number:
PCT/CN2018/117011
Publication Date:
May 28, 2020
Filing Date:
November 22, 2018
Export Citation:
Assignee:
SUZHOU KANOVA BIOPHARMACEUTICAL CO LTD (CN)
BEIJING KANOVA BIOPHARMACEUTICAL CO LTD (CN)
BEIJING KANOVA BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07K16/30; A61K39/00; A61K39/395; A61P35/00; C07K16/28; C07K19/00; C12N1/15; C12N5/10; C12N15/09
Domestic Patent References:
| WO2016033225A2 | 2016-03-03 | |||
| WO2016106004A1 | 2016-06-30 |
Foreign References:
| US20180185510A1 | 2018-07-05 |
Other References:
See also references of EP 3883970A4
Attorney, Agent or Firm:
BEIJING CAI HE LAW FIRM (CN)
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