ANTI-HUMAN HEMOGLOBIN β-CHAIN MONOCLONAL ANTIBODY OR ANTIGEN-BINDING FRAGMENT THEREOF, METHOD FOR DETECTING HUMAN HEMOGLOBIN AND/OR GLYCOSYLATED HUMAN HEMOGLOBIN, KIT FOR DETECTING HUMAN HEMOGLOBIN AND/OR GLYCOSYLATED HUMAN HEMOGLOBIN, AND PEPTIDE

Title:

Document Type and Number:

WIPO Patent Application WO/2023/195347

Kind Code:

A1

Abstract:

An anti-human hemoglobin β-chain monoclonal antibody or an antigen-binding fragment thereof, according to the present invention, binds to (a) 15-29th or (b) 37-66th amino acid regions in the amino acid sequence of a human hemoglobin β-chain, said amino acid sequence being indicated by sequence number 1.

Inventors:

KATSUMI MARINA (JP)
SHIMOMOTO MASAKO (JP)
OGASAWARA SHINYA (JP)

Application Number:

PCT/JP2023/011456

Publication Date:

October 12, 2023

Filing Date:

March 23, 2023

Export Citation:

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Assignee:

DENKA COMPANY LTD (JP)

International Classes:

C07K16/18; G01N33/53; G01N33/531; G01N33/72

Domestic Patent References:

WO2010067611A1	2010-06-17
WO2014112318A1	2014-07-24

Other References:

KAZIM, A. LATIF ET AL.: "Prediction and Confirmation by Synthesis of Two Antigenic Sites in Human Haemoglobin by Extrapolation from the Known Antigenic Structure of Sperm-Whale Myoglobin", BIOCHEM. J., vol. 167, 1977, pages 275 - 278, XP009549174
YOSHIOKA N, ATASSI M Z: "Antigenic structure of human haemoglobin. Localization of the antigenic sites of the β-chain in three host species by synthetic overlapping peptides representing the entire chain", BIOCHEMICAL JOURNAL, PUBLISHED BY PORTLAND PRESS ON BEHALF OF THE BIOCHEMICAL SOCIETY., GB, vol. 234, no. 2, 1 March 1986 (1986-03-01), GB , pages 441 - 447, XP009549172, ISSN: 0264-6021, DOI: 10.1042/bj2340441

Attorney, Agent or Firm:

HASEGAWA Yoshiki et al. (JP)

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