Title:
ANTI-PD-1 ANTIBODY AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/125289
Kind Code:
A1
Abstract:
The present invention belongs to the field of biomedicine. Provided are an anti-PD-1 antibody or an antigen-binding fragment thereof, and a biological material, a composition, a conjugate, an antibody derivative and a kit of the antibody or the antigen-binding fragment thereof, as well as the uses thereof. The anti-PD-1 antibody may specifically bind to PD-1, block interactions between PD-1 and PD-L1 or PD-L2, activate an immune response, and has good developability.
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Inventors:
LI YONG (CN)
SUI RUIRUI (CN)
XI YUE (CN)
SONG FEI (CN)
JIANG DIANDONG (CN)
LEUNG STEWART (CN)
SU YUNPENG (CN)
SUI RUIRUI (CN)
XI YUE (CN)
SONG FEI (CN)
JIANG DIANDONG (CN)
LEUNG STEWART (CN)
SU YUNPENG (CN)
Application Number:
PCT/CN2022/141424
Publication Date:
July 06, 2023
Filing Date:
December 23, 2022
Export Citation:
Assignee:
HC BIOPHARMA INC (CN)
International Classes:
C07K16/40; A61K35/17; A61K39/00; A61P35/00; C07K14/725
Foreign References:
| CN112979802A | 2021-06-18 | |||
| CN108290957A | 2018-07-17 | |||
| CN107531801A | 2018-01-02 | |||
| CN112672753A | 2021-04-16 | |||
| CN113164621A | 2021-07-23 | |||
| CN104411720A | 2015-03-11 |
Other References:
SUN YU-TING, GUAN WEN-LONG, ZHAO QI, WANG DE-SHEN, LU SHI-XUN, HE CAI-YUN, CHEN SHUANG-ZHEN, WANG FENG-HUA, LI YU-HONG, ZHOU ZHI-W: "PD-1 antibody camrelizumab for Epstein-Barr virus-positive metastatic gastric cancer: a single-arm, open-label, phase 2 trial", AMERICAN JOURNAL OF CANCER RESEARCH, E-CENTURY PUBLISHING CORPORATION, US, vol. 11, no. 10, 15 October 2021 (2021-10-15), US , pages 5006 - 5015, XP093075965, ISSN: 2156-6976
Attorney, Agent or Firm:
SINO-CREATIVITY INTELLECTUAL PROPERTY LAW FIRM (CN)
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