ANTI PD-L1 ANTIBODY AND USE THEREOF - MABWELL SHANGHAI BIOSCIENCE CO LTD

Title:

ANTI PD-L1 ANTIBODY AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/136489

Kind Code:

A1

Abstract:

Provided in the present invention are an antibody against PD-L1 or a fragment thereof, a nucleic acid encoding the antibody or the fragment thereof, a composition containing the antibody or the fragment thereof and the use thereof in the treatment of diseases. The antibody or the fragment thereof provided in the present invention can specifically bind to human PD-L1, block the binding of PD-L1 and PD-1, have a strong ADCC effect on target cells and significantly inhibit tumor growth.

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Inventors:

WANG SHUANG (CN)
JIAO SHASHA (CN)
WANG RONGJUAN (CN)
ZHANG CHANG (CN)

Application Number:

PCT/CN2020/142038

Publication Date:

July 08, 2021

Filing Date:

December 31, 2020

Export Citation:

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Assignee:

MABWELL SHANGHAI BIOSCIENCE CO LTD (CN)

International Classes:

C07K16/28; A61K39/395; A61P35/00; C07K19/00; C12N5/10; C12N15/13; C12N15/63

Foreign References:

CN109970857A	2019-07-05
CN110337449A	2019-10-15
CN110156892A	2019-08-23
CN110156895A	2019-08-23
CN109641960A	2019-04-16
CN109467601A	2019-03-15
CN109311985A	2019-02-05
CN110194798A	2019-09-03

Attorney, Agent or Firm:

LEADING INTELLECTUAL PROPERTY FIRM (CN)

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