Title:
ANTI-PD-L1 ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/061272
Kind Code:
A1
Abstract:
Provided are an anti-PD-L1 antibody, a pharmaceutical composition comprising the antibody, and use thereof. Further provided are a polynucleotide encoding the antibody, an expression vector, and a method for producing the antibody.
Inventors:
YAN XINTIAN (CN)
LANG GUOJUN (CN)
LI SHUANGQI (CN)
FANG XIAOPENG (CN)
KONG CHAO (CN)
LANG GUOJUN (CN)
LI SHUANGQI (CN)
FANG XIAOPENG (CN)
KONG CHAO (CN)
Application Number:
PCT/CN2023/120060
Publication Date:
March 28, 2024
Filing Date:
September 20, 2023
Export Citation:
Assignee:
SANYOU BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
C07K16/28; A61K39/395; A61P35/00; C12N15/13
Domestic Patent References:
| WO2022105832A1 | 2022-05-27 | |||
| WO2017020801A1 | 2017-02-09 | |||
| WO2022042715A1 | 2022-03-03 |
Foreign References:
| CN111848800A | 2020-10-30 | |||
| CN112745391A | 2021-05-04 | |||
| CN113825774A | 2021-12-21 | |||
| CN114430746A | 2022-05-03 | |||
| CN111328286A | 2020-06-23 |
Other References:
LIU JINLONG; HONG HAOFEI; SHI JIE; XIE YUNTIAN; LU ZHONGKAI; LIU ZHICHENG; ZHOU ZHIFANG; BIAN ZEHUA; HUANG ZHAOHUI; WU ZHIMENG: "Dinitrophenol-mediated modulation of an anti-PD-L1 VHH for Fc-dependent effector functions and prolonged serum half-life", EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, ELSEVIER AMSTERDAM, NL, vol. 165, 10 July 2021 (2021-07-10), NL , XP086725186, ISSN: 0928-0987, DOI: 10.1016/j.ejps.2021.105941
LI YUMEI, WU LINGJUN, LIU YUEYING, MA SIWEN, HUANG BIYI, FENG XIANJING, WANG HUI: "A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells", TRANSLATIONAL ONCOLOGY, NEOPLASIA PRESS, UNITED STATES, vol. 21, 26 April 2022 (2022-04-26), United States , pages 101424, XP093148738, ISSN: 1936-5233, DOI: 10.1016/j.tranon.2022.101424
LI YUMEI, WU LINGJUN, LIU YUEYING, MA SIWEN, HUANG BIYI, FENG XIANJING, WANG HUI: "A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells", TRANSLATIONAL ONCOLOGY, NEOPLASIA PRESS, UNITED STATES, vol. 21, 26 April 2022 (2022-04-26), United States , pages 101424, XP093148738, ISSN: 1936-5233, DOI: 10.1016/j.tranon.2022.101424
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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