Title:
ANTI-PD-L1 NANOBODIES
Document Type and Number:
WIPO Patent Application WO/2024/104373
Kind Code:
A1
Abstract:
Provided are affinity-maturated single domain anti-PD-L1 antibodies and polypeptides, such as multispecific antibodies and chimeric antigen receptors, that include these single domain antibodies. These antibodies, including their humanized counterparts, exhibited superior activities and are suitable for use in various multispecific antibody formats. Methods of using the antibodies or polypeptides for treating and diagnosing diseases such as cancer and infectious diseases are also provided.
Inventors:
LI JIAN (CN)
YANG HUI (CN)
YANG HUI (CN)
Application Number:
PCT/CN2023/131749
Publication Date:
May 23, 2024
Filing Date:
November 15, 2023
Export Citation:
Assignee:
I MAB BIOPHARMA CO LTD (CN)
International Classes:
C07K16/28; A61K39/395; A61P35/00; C12N15/13
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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