ANTI-PSMA ANTIBODIES, VARIANTS, AND USES THEREOF.

Title:

ANTI-PSMA ANTIBODIES, VARIANTS, AND USES THEREOF.

Document Type and Number:

WIPO Patent Application WO/2023/192842

Kind Code:

A3

Abstract:

PSMA is a prostate cancer marker, and cancers with higher malignancy or metastasis, or resistant to androgen deprivation therapy, usually express much higher PSMA. The present invention relates to the improved anti-PSMA antibodies or antigen-binding fragments thereof, related nucleic acids, vectors, cells, compositions, kits, and the methods of use thereof.

Inventors:

ZHAO AIZHI (US)
WEN WEIHONG (CN)

Application Number:

PCT/US2023/065017

Publication Date:

November 09, 2023

Filing Date:

March 28, 2023

Export Citation:

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Assignee:

ORIMABS LTD (US)

International Classes:

C07K16/30; A61K39/395; A61P35/00; G01N33/574

Foreign References:

US20210277141A1	2021-09-09
US20110076279A1	2011-03-31
US20210115135A1	2021-04-22

Other References:

DATABASE PROTEIN ANONYMOUS : "immunoglobulin light chain junction region, partial [Homo sapiens]", XP093109688, retrieved from NCBI
DATABASE PROTEIN ANONYMOUS : "immunoglobulin light chain variable region, partial [Homo sapiens]", XP093109690, retrieved from NCBI

Attorney, Agent or Firm:

HAO, Jianming et al. (US)

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