Title:
ANTI-ROR1 ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/025343
Kind Code:
A1
Abstract:
The present invention relates to: a receptor tyrosine kinase like orphan receptor 1 (ROR 1) antibody or an antigen-binding fragment thereof; a nucleic acid encoding same; a recombinant expression vector carrying the nucleic acid; a host cell transinfected with the recombinant expression vector; a method for preparing the antibody or the antigen-binding fragment thereof; a bi- or multi-specific antibody bearing the antibody or the antigen-binding fragment thereof; an immune cell-engaging bi- or multi-specific antibody; an antibody-drug conjugate (ADC) in which the antibody or the antigen-binding fragment thereof is bound to a drug; a chimeric antigen receptor (CAR) containing the scFv of the antibody as an antigen-binding site of an extracellular domain; an immune cell having the chimeric antigen receptor introduced thereinto; a composition for combination therapy including the antibody or the antigen-binding fragment thereof; a composition for preventing or treating cancer; and a method for preventing or treating cancer.
Inventors:
MIN BYEONGKWI (KR)
YOO MINYOUNG (KR)
KIM JIWON (KR)
KIM JONGBIN (KR)
YOO MINYOUNG (KR)
KIM JIWON (KR)
KIM JONGBIN (KR)
Application Number:
PCT/KR2023/010847
Publication Date:
February 01, 2024
Filing Date:
July 26, 2023
Export Citation:
Assignee:
AIMED BIO INC (KR)
International Classes:
C07K16/28; A61K39/00; A61K47/68; A61P35/00
Domestic Patent References:
| WO2017136607A1 | 2017-08-10 | |||
| WO2021159029A1 | 2021-08-12 | |||
| WO2022129622A1 | 2022-06-23 |
Foreign References:
| KR20180069067A | 2018-06-22 | |||
| KR20180101554A | 2018-09-12 | |||
| KR20200143470A | 2020-12-23 |
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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