Title:
ANTI-TUMOR COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2021/170138
Kind Code:
A1
Abstract:
An anti-tumor composition, comprising: (A) Bifidobacterium longum and (B) an immune checkpoint inhibitor such as a PD-1 inhibitor, a PD-L1 inhibitor, and a CTLA-4 inhibitor. Also provided is a use of Bifidobacterium longum in preparing a drug for treating a tumor, wherein Bifidobacterium longum can be used in combination with an immune checkpoint inhibitor preparation.
Inventors:
XU XIAOFEN (CN)
SUN NINGYUN (CN)
LIANG XI (CN)
YU HONGJING (CN)
WEN BIN (CN)
YIN PEIJUN (CN)
SUN NINGYUN (CN)
LIANG XI (CN)
YU HONGJING (CN)
WEN BIN (CN)
YIN PEIJUN (CN)
Application Number:
PCT/CN2021/078437
Publication Date:
September 02, 2021
Filing Date:
March 01, 2021
Export Citation:
Assignee:
SPH SINE PHARMACEUTICAL LABORATORIES CO LTD (CN)
International Classes:
A61K35/745; A61K35/00; A61K45/06
Domestic Patent References:
| WO2018226690A1 | 2018-12-13 |
Foreign References:
| CN111096982A | 2020-05-05 | |||
| CN106110322A | 2016-11-16 | |||
| CN107847530A | 2018-03-27 | |||
| CN110063970A | 2019-07-30 | |||
| CN103830278A | 2014-06-04 | |||
| CN103131647A | 2013-06-05 | |||
| CN101244090A | 2008-08-20 | |||
| CN101244089A | 2008-08-20 | |||
| CN1223865A | 1999-07-28 | |||
| US6368591B2 | 2002-04-09 |
Other References:
MA WEIDONG, XU LIN，JIANG FENG: "Ｒesearch progress of Gut microbiota in regulating the therapeutic effect of cancer", CHINESE JOURNAL OF SURGICAL ONCOLOGY, vol. 11, no. 3, 1 June 2019 (2019-06-01), pages 217 - 220, XP055841833, ISSN: 1674-4136, DOI: 10．3969 /j．issn．1674－4136．2019．03．016
See also references of EP 4112065A4
See also references of EP 4112065A4
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (CN)
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