Title:
ANTI-VIRAL COMPOSITION COMPRISING PLACENTA-DERIVED MATERIAL
Document Type and Number:
WIPO Patent Application WO/2021/210852
Kind Code:
A1
Abstract:
The present invention relates to an anti-viral composition comprising at least one placenta-derived substance selected from the group consisting of placenta-derived cells, mesenchymal stem cells, extracellular vesicles, exosomes, microparticles, total RNA, and miRNA. The placenta-derived cells, mesenchymal stem cells, extracellular vesicles, exosomes, microparticles, total RNA, or miRNA, when administered to virus-infected cells, inhibited virus viability in a dose-dependent manner and, as such, can be advantageously used for preventing or treating viral infections.
Inventors:
YOO YOUNG HYO (KR)
HAN HAE JUNG (KR)
LIM MINJU (KR)
JEONG KYEONGSOO (KR)
KIM EUN-HA (KR)
KIM SE MI (KR)
HAN HAE JUNG (KR)
LIM MINJU (KR)
JEONG KYEONGSOO (KR)
KIM EUN-HA (KR)
KIM SE MI (KR)
Application Number:
PCT/KR2021/004465
Publication Date:
October 21, 2021
Filing Date:
April 09, 2021
Export Citation:
Assignee:
GREEN CROSS WELLBEING CORP (KR)
International Classes:
A61K35/50; A01N63/10; A23L33/17; A61K8/98; A61K31/7088; A61K35/28; A61P31/12; A61P31/14; A61Q17/00; A61Q19/00
Domestic Patent References:
| WO2020051362A1 | 2020-03-12 |
Foreign References:
| CN108143750A | 2018-06-12 | |||
| JP2017536096A | 2017-12-07 |
Other References:
JANE RIDLE: "Stem cells from a baby’s placenta may save life of coronavirus victim in NJ", 13 April 2020 (2020-04-13), pages 1 - 5, XP055857829, Retrieved from the Internet
MAAYAN JAFFE-HOFFMAN: "Israeli company uses placenta cells to treat critical COVID-19 patients", pages 1 - 3, XP055857841, Retrieved from the Internet
MOTOHIRO KOMAKI, YURI NUMATA, CHIKAKO MORIOKA, IZUMI HONDA, MASAYUKI TOOI, NAOKI YOKOYAMA, HIROHITO AYAME, KENGO IWASAKI, ATSUKO T: "Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis", STEM CELL RESEARCH & THERAPY, vol. 8, 219, 1 December 2017 (2017-12-01), pages 1 - 12, XP055857846, DOI: 10.1186/s13287-017-0660-9
MAAYAN JAFFE-HOFFMAN: "Israeli company uses placenta cells to treat critical COVID-19 patients", pages 1 - 3, XP055857841, Retrieved from the Internet
MOTOHIRO KOMAKI, YURI NUMATA, CHIKAKO MORIOKA, IZUMI HONDA, MASAYUKI TOOI, NAOKI YOKOYAMA, HIROHITO AYAME, KENGO IWASAKI, ATSUKO T: "Exosomes of human placenta-derived mesenchymal stem cells stimulate angiogenesis", STEM CELL RESEARCH & THERAPY, vol. 8, 219, 1 December 2017 (2017-12-01), pages 1 - 12, XP055857846, DOI: 10.1186/s13287-017-0660-9
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
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