ANTIBACTERIAL COMPOSITIONS CONTAINING OF OXAPENEM-3-CARBOXYLIC ACIDS AND ANTIBIOTICS

Title:

ANTIBACTERIAL COMPOSITIONS CONTAINING OF OXAPENEM-3-CARBOXYLIC ACIDS AND ANTIBIOTICS

Document Type and Number:

WIPO Patent Application WO2002074287

Kind Code:

A3

Abstract:

Disclosed is use of an oxenpenem-3-carboxylic acid of structure (I) or (II) as define above, in combination with an antibiotic and a pharmaceutically acceptable excipient, to prepare a medicament to treat an infection in a human or animal subject caused by a bacterium which does not produce a significant amount of beta -lactamase.

Inventors:

SIMPSON IAIN (GB)
PFAENDLER HANS RUDOLF (DE)

Application Number:

PCT/GB2002/001162

Publication Date:

May 01, 2003

Filing Date:

March 14, 2002

Export Citation:

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Assignee:

AMURA LTD (GB)
SIMPSON IAIN (GB)
PFAENDLER HANS RUDOLF (DE)

International Classes:

A61K31/43; A61K45/06; A61P31/04; (IPC1-7): A61K31/546; A61K31/423; A61K38/14; A61P31/04

Foreign References:

US5108747A

1992-04-28

Other References:

PFAENDLER, HANS RUDOLF ET AL: "Synthesis and antibacterial activity of (1'R,5R,6R)-2-tert-butyl-6-(1'- hydroxyethyl)oxapenem-3-carboxylic acid", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (1993), 3(11), 2211-18, XP008012641

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