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Title:
ANTIBODIES, IMMOBILIZED ANTIBODIES USING SAME, ANTIBODY COMPOSITION, REAGENT FOR IMMUNOLOGICAL MEASUREMENT, IMMUNOLOGICAL MEASUREMENT METHOD, AND METHOD FOR IMPROVING ANTIGEN RESPONSIVENESS OF ANTIBODIES
Document Type and Number:
WIPO Patent Application WO/2023/032886
Kind Code:
A1
Abstract:
Provided are antibodies for use in an immunological measurement method, the antibodies including an Fc region and being such that at least some of the sugar chains included in the Fc region are removed.

Inventors:
KOZUKA NAOYUKI (JP)
Application Number:
PCT/JP2022/032335
Publication Date:
March 09, 2023
Filing Date:
August 29, 2022
Export Citation:
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Assignee:
EIKEN CHEMICAL (JP)
International Classes:
C07K16/00; C07K17/00; G01N33/531
Domestic Patent References:
WO2020061159A12020-03-26
Foreign References:
JPH0348700A1991-03-01
US20200115439A12020-04-16
US20200390879A12020-12-17
JP3439780B22003-08-25
Other References:
PAREKH R. B.; DWEK R. A.; SUTTON B. J.; FERNANDES D. L.; LEUNG A.; STANWORTH D.; RADEMACHER T. W.; MIZUOCHI T.; TANIGUCHI T.; MATS: "Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG", NATURE, NATURE PUBLISHING GROUP UK, LONDON, vol. 316, no. 6027, 1 August 1985 (1985-08-01), London, pages 452 - 457, XP037115374, ISSN: 0028-0836, DOI: 10.1038/316452a0
KAGAKU TO SEIBUTSU, vol. 30, no. 4, 1992, pages 236 - 243
GLYCOBIOLOGY, vol. 19, 2009, pages 936 - 949
J. BIOTECHNOL., vol. 188, 2014, pages 88 - 96
MABS, vol. 11, 2019, pages 350 - 372
J. BIOL. CHEM., vol. 277, 2002, pages 26733 - 26740
J. BIOL. CHEM., vol. 291, 2016, pages 9356 - 9370
KABAT E. A. ET AL.: "Sequences of Proteins of Immunological Interest", 1991, NATIONAL INSTITUTES OF HEALTH
KUNKEL, PROC. NATL. ACAD. SCI. USA, vol. 82, 1985, pages 488 - 492
Attorney, Agent or Firm:
CENTCREST IP ATTORNEYS (JP)
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