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Title:
ANTIBODY-BINDING POLYPEPTIDE, ANTIBODY-BINDING FUSION POLYPEPTIDE, AND ADSORBENT MATERIAL
Document Type and Number:
WIPO Patent Application WO/2016/052073
Kind Code:
A1
Abstract:
 Provided are an antibody-binding polypeptide shown by any one of SEQ ID NOS: 1-18, and an adsorbent material for an antibody or antibody derivative in which this antibody-binding polypeptide is immobilized on a water-insoluble carrier This antibody-binding polypeptide and adsorbent material have exceptional alkali resistance and stability over time together with exceptional antibody-binding properties and selectivity.

Inventors:
MINAMI KOICHI (JP)
Application Number:
PCT/JP2015/075157
Publication Date:
April 07, 2016
Filing Date:
September 04, 2015
Export Citation:
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Assignee:
FUJIFILM CORP (JP)
International Classes:
C07K4/00; C07K7/06; C07K7/08; C07K14/00; C07K17/00
Domestic Patent References:
WO1997037677A11997-10-16
WO2012133342A12012-10-04
Foreign References:
JPS62126199A1987-06-08
JPH02501985A1990-07-05
JP2011521653A2011-07-28
Other References:
SINHA PRATIMA ET AL.: "FUNCTIONAL DICHOTOMY OF A 20-MERAND 16-MER PEPTIDE DERIVED FROM STAPHYLOCOCCUS AUREUS PROTEIN A: IMPORTANCE OF AMINOACID SEQUENCE", IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, vol. 24, no. 2, 2002, pages 199 - 210, XP008071866, DOI: doi:10.1081/IPH-120003750
ZHANG JUN ET AL.: "Protein G, Protein A and Protein A-Derived Peptides Inhibit the Agitation Induced Aggregation of IgG", MOLECULAR PHARMACEUTICS, vol. 9, no. 3, 2012, pages 622 - 628, XP055370202
SINHA PRATIMA ET AL.: "A Minimized Fc Binding Peptide from Protein A Induces Immunocyte Proliferation and Evokes Th1-Type Response in Mice", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 258, 1999, pages 141 - 147, XP055173070
SENGUPTA JAYATI ET AL.: "Molecular Modeling and Experimental Approaches toward Designing a Minimalist Protein Having Fc-binding Activity of Staphylococcal Protein A", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 256, 1999, pages 6 - 12, XP055370212
SUGITA TOMOYA ET AL.: "Screening of peptide ligands that bind to the Fc region of IgG using peptide array and its application to affinity purification of antibody", BIOCHEMICAL ENGINEERING JOURNAL, vol. 79, 2013, pages 33 - 40, XP028733013, DOI: doi:10.1016/j.bej.2013.06.017
KAKOI SAYAKA ET AL.: "Identification of mouse IgG antibody-binding peptide by screening from T7 phage random peptide library", PEPTIDE SCIENCE, 2010, pages 73, XP008184535
See also references of EP 3202774A4
Attorney, Agent or Firm:
WATANABE Mochitoshi et al. (JP)
Mochitoshi Watanabe (JP)
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