ANTIBODY BINDING SPECIFICALLY TO SARS-COV-2 S PROTEIN OR ANTIGEN-BINDING FRAGMENT THEREOF, AND USES THEREOF

Title:

ANTIBODY BINDING SPECIFICALLY TO SARS-COV-2 S PROTEIN OR ANTIGEN-BINDING FRAGMENT THEREOF, AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2022/231320

Kind Code:

A1

Abstract:

The present invention relates to an anti-SARS-CoV-2 S protein antibody or an antigen-binding fragment thereof, and therapeutic and diagnostic uses thereof. The anti-SARS-CoV-2 S protein antibody or antigen-binding fragment thereof according to the present invention can bind specifically to the S protein, which plays an important role in the infiltration of SARS-CoV-2 into host cells, to inhibit the infection of SARS-CoA-2, and thus can be advantageously used as a therapeutic agent for COVID-19 and as a diagnostic agent and diagnostic kit for COVID-19.

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Inventors:

LEE SUKMOOK (KR)
KIM JI WOONG (KR)
HEO KYUN (KR)
CHO YEABIN (KR)
KIM HYUN JUNG (KR)
CHOI HYELIM (KR)
YANG HARIM (KR)
SHIN HA GYEONG (KR)

Application Number:

PCT/KR2022/006054

Publication Date:

November 03, 2022

Filing Date:

April 27, 2022

Export Citation:

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Assignee:

UNIV KOOKMIN IND ACAD COOP FOUND (KR)

International Classes:

C07K16/10; A61K39/00; A61P31/14; G01N33/563; G01N33/569

Foreign References:

KR102205028B1	2021-01-20
US10787501B1	2020-09-29
KR102233689B1	2021-03-30
EP3809137A1	2021-04-21

Other References:

KIM CHEOLMIN, RYU DONG-KYUN, LEE JIHUN, KIM YOUNG-IL, SEO JI-MIN, KIM YEON-GIL, JEONG JAE-HEE, KIM MINSOO, KIM JONG-IN, KIM PANKYE: "A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein", NATURE COMMUNICATIONS, vol. 12, no. 1, 1 December 2021 (2021-12-01), XP055889424, DOI: 10.1038/s41467-020-20602-5

Attorney, Agent or Firm:

KONG, Byung Wook (KR)

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