Title:
ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 24P4C12 PROTEINS
Document Type and Number:
WIPO Patent Application WO/2010/111018
Kind Code:
A8
Abstract:
Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
Inventors:
GUDAS JEAN (US)
JAKOBOVITS AYA (US)
AN ZILI (US)
MORRISON ROBERT KENDALL (US)
MORRISON KAREN JANE MEYRICK (US)
JIA XIAO-CHI (US)
BENJAMIN DENNIS (US)
MOSER RUTH (US)
SENTER PETER (US)
JAKOBOVITS AYA (US)
AN ZILI (US)
MORRISON ROBERT KENDALL (US)
MORRISON KAREN JANE MEYRICK (US)
JIA XIAO-CHI (US)
BENJAMIN DENNIS (US)
MOSER RUTH (US)
SENTER PETER (US)
Application Number:
PCT/US2010/026429
Publication Date:
March 03, 2011
Filing Date:
March 05, 2010
Export Citation:
Assignee:
AGENSYS INC (US)
SEATTLE GENETICS INC (US)
GUDAS JEAN (US)
JAKOBOVITS AYA (US)
AN ZILI (US)
MORRISON ROBERT KENDALL (US)
MORRISON KAREN JANE MEYRICK (US)
JIA XIAO-CHI (US)
BENJAMIN DENNIS (US)
MOSER RUTH (US)
SENTER PETER (US)
SEATTLE GENETICS INC (US)
GUDAS JEAN (US)
JAKOBOVITS AYA (US)
AN ZILI (US)
MORRISON ROBERT KENDALL (US)
MORRISON KAREN JANE MEYRICK (US)
JIA XIAO-CHI (US)
BENJAMIN DENNIS (US)
MOSER RUTH (US)
SENTER PETER (US)
International Classes:
C12P21/08; A61K39/00
Attorney, Agent or Firm:
MURASHIGE, Kate., H. et al. (12531 High Bluff Drive Suite 10, San Diego CA, US)
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