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Title:
ANTIBODY-LINKED IMMUNO-SEDIMENTATION AGENT AND METHOD OF ISOLATING A TARGET FROM A SAMPLE USING SAME
Document Type and Number:
WIPO Patent Application WO/2012/083020
Kind Code:
A3
Abstract:
The present disclosure is directed to antibody-linked immuno-sedimentation agent, the antibody being linked to a sedimentation agent by a non-antigen binding region of the antibody, and a method of isolating a target from a sample using the antibody-linked immuno-sedimentation agent. The methods involve forming a mixture including a sample with an antibody linked immuno-sedimentation agent and red blood cells under conditions sufficient to form red blood cell rouleaux and allow antibody-antigen binding.

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Inventors:
DINGES WARREN L (US)
Application Number:
PCT/US2011/065157
Publication Date:
December 20, 2012
Filing Date:
December 15, 2011
Export Citation:
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Assignee:
CYTOSED INC (US)
DINGES WARREN L (US)
International Classes:
G01N33/537
Domestic Patent References:
WO2006094810A22006-09-14
WO2000073794A22000-12-07
Other References:
BJÖRN NEU ET AL: "Depletion-Mediated Red Blood Cell Aggregation in Polymer Solutions", BIOPHYSICAL JOURNAL, vol. 83, no. 5, 1 November 2002 (2002-11-01), pages 2482 - 2490, XP055026742, ISSN: 0006-3495, DOI: 10.1016/S0006-3495(02)75259-4
Attorney, Agent or Firm:
HARWOOD, Melissa M. et al. (777 6th Street NW,Suite 110, Washington District of Columbia, US)
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