Title:
ANTIBODY, NUCLEIC ACID, CELL, AND PHARMACEUTICAL
Document Type and Number:
WIPO Patent Application WO/2024/085081
Kind Code:
A1
Abstract:
Provided is an antibody that specifically binds to the extracellular domain of human LPA1 but does not specifically bind to the extracellular domain of human LPA2 or the extracellular domain of human LPA3. The antibody preferably has activity to block LPA1-dependent cellular function. Also provided are: an nucleic acid encoding the antibody; a cell containing sthe nucleic acid; and a pharmaceutical containing the antibody as an active ingredient.
Inventors:
HIKICHI MEGUMI (JP)
ASHIDA MASAMI (JP)
NAKAGAWA MIKI (JP)
SHINAGAWA MASAHIKO (JP)
TANAKA RYOMA (JP)
TAKAYAMA KIYOSHI (JP)
AOKI JUNKEN (JP)
ASHIDA MASAMI (JP)
NAKAGAWA MIKI (JP)
SHINAGAWA MASAHIKO (JP)
TANAKA RYOMA (JP)
TAKAYAMA KIYOSHI (JP)
AOKI JUNKEN (JP)
Application Number:
PCT/JP2023/037183
Publication Date:
April 25, 2024
Filing Date:
October 13, 2023
Export Citation:
Assignee:
NB HEALTH LABORATORY CO LTD (JP)
THE UNIV OF TOKYO (JP)
THE UNIV OF TOKYO (JP)
International Classes:
C12N15/13; A61K39/395; A61K47/68; A61P1/00; A61P1/16; A61P9/00; A61P11/00; A61P13/12; A61P17/00; A61P25/04; A61P27/02; A61P29/00; A61P35/00; C07K16/28; C07K16/46; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Attorney, Agent or Firm:
FUJITA Takashi et al. (JP)
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