ANTIBODY SPECIFICALLY RECOGNIZING C5A AND APPLICATION OF ANTIBODY - STAIDSON BEIJING BIOPHARMACEUTICALS CO LTD

Title:

ANTIBODY SPECIFICALLY RECOGNIZING C5A AND APPLICATION OF ANTIBODY

Document Type and Number:

WIPO Patent Application WO/2023/186054

Kind Code:

A1

Abstract:

The present invention relates to an antibody specifically recognizing C5a. The antibody has high binding activity to human C5a or human C5a-desArg. Moreover, the present invention further relates to a nucleotide sequence encoding the antibody, a vector and a cell comprising the nucleotide sequence, a pharmaceutical composition comprising the antibody, a use of the antibody in the preparation of a drug for treating autoimmune diseases and inflammation, cancer, pain, respiration and/or transplantation-related diseases, and a use of the antibody or a conjugate thereof in the preparation of a kit for detecting the presence or level of C5a.

More Like This:

WO/2001/038374	TUMOUR SUPPRESSOR FACTOR
JP6514762	Compositions and methods for diagnosing and treating diseases associated with neurite degeneration
WO/2006/083689	ANTI A BETA ANTIBODY FORMULATION

Inventors:

LI ZHONG (CN)
MIAO LIUYANG (CN)
WU FEILIN (CN)

Application Number:

PCT/CN2023/085301

Publication Date:

October 05, 2023

Filing Date:

March 31, 2023

Export Citation:

Click for automatic bibliography generation Help

Assignee:

STAIDSON BEIJING BIOPHARMACEUTICALS CO LTD (CN)

International Classes:

C07K16/18; A61K39/00; A61K39/12; A61K39/215; A61K39/395; A61P13/00; A61P35/00; A61P37/00; A61P37/06; C12N5/10; C12N15/13; C12N15/63; C12N15/64

Foreign References:

CN103201289A	2013-07-10
CN102741283A	2012-10-17
AU2013200223A1	2013-01-31
HK1029595A1	2001-04-06

Other References:

CHEN CHEN, LV RUO-YUN, WEI JING-SHUANG: "Role of C5a in inflammatory reaction and development of anti-C5a antibody drugs", CHINESE JOURNAL OF BIOLOGICALS, CHINESE PREVENTIVE MEDICINE ASSOCIATION, CHINA, vol. 28, no. 5, 31 May 2015 (2015-05-31), China , XP055889587, ISSN: 1004-5503
CAROLINE S. COLLEY, BOJANA POPOVIC, SUDHARSAN SRIDHARAN, JUDIT E. DEBRECZENI, DAVID HARGEAVES, MICHAEL FUNG, LING–LING AN, B: "Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors", MABS, US , pages 1 - 14, XP055425527, ISSN: 1942-0862, DOI: 10.1080/19420862.2017.1384892

Download PDF:

View/Download PDF PDF Help

Previous Patent: FLEXIBLE NEURAL ELECTRODE COMPOSITE STRUCTURE AND MANUFACTURING AND IMPLANTATION METHOD THEREFOR, AN...

Next Patent: DRILLING TOOL, DRILLING METHOD AND DRILLING GUIDING METHOD