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Title:
ANTICANCER AGENT, PRODRUG OF ANTICANCER AGENT, METHOD FOR KILLING CANCER CELLS IN VITRO, CANCER THERAPY METHOD AND CANCER THERAPY DEVICE
Document Type and Number:
WIPO Patent Application WO/2023/068325
Kind Code:
A1
Abstract:
Provided is an anticancer agent containing nitrogen 15 and also containing a substance that is accumulated specifically in cancer cells. Also provided is a method for killing cancer cells in vitro, said method comprising accumulating nitrogen 15 in cancer cells in vitro and irradiating the cancer cells with proton beams in vitro. Also provided is a cancer therapy method comprising accumulating nitrogen 15 in cancer cells of a human or a non-human animal and irradiating the human or non-human animal with proton beams.

Inventors:
IWATA YASUSHI (JP)
MATSUI HIROFUMI (JP)
SUZUKI IWANE (JP)
SUZUKI YUJI (JP)
TOMITA KANAKO (JP)
YANG TIANJING (JP)
IKEDA TAKAFUMI (JP)
KUROKAWA HIROMI (JP)
Application Number:
PCT/JP2022/039079
Publication Date:
April 27, 2023
Filing Date:
October 20, 2022
Export Citation:
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Assignee:
AIST (JP)
UNIV TSUKUBA (JP)
TAIYO SERVICE INC (JP)
International Classes:
A61K41/00; A61K31/197; A61K31/513; A61K45/00; A61K47/68; A61N5/10; A61P35/00; C12N5/09
Domestic Patent References:
WO2021029391A12021-02-18
WO2018237241A12018-12-27
Foreign References:
JPH1112197A1999-01-19
CN112834680A2021-05-25
JP2018527402A2018-09-20
JP2018058822A2018-04-12
JP2003096098A2003-04-03
JP2008022994A2008-02-07
JP2016216404A2016-12-22
JP2014177421A2014-09-25
Other References:
IWATA, YASUSHI: "Developing unique medical technology to link medical institutions, companies, universities and government offices", JSLSM JOURNAL, vol. 42, no. 3, 30 September 2021 (2021-09-30), pages 138, XP009545374
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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