Title:
ANTICANCER COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2020/060247
Kind Code:
A1
Abstract:
Disclosed is an anticancer formula composition comprising trabedersen and IL-2.
Inventors:
KIM TAE HUN (KR)
PARK JUN EUI (KR)
LEE JEONG MIN (KR)
PARK JUN EUI (KR)
LEE JEONG MIN (KR)
Application Number:
PCT/KR2019/012178
Publication Date:
March 26, 2020
Filing Date:
September 19, 2019
Export Citation:
Assignee:
AUTOTELIC BIO INC (KR)
International Classes:
A61K31/7088; A61K38/20; A61P35/00
Domestic Patent References:
| WO2018045346A1 | 2018-03-08 | |||
| WO2017218544A1 | 2017-12-21 |
Foreign References:
| US20070184020A1 | 2007-08-09 |
Other References:
PARK, J. ET AL.: "Combination delivery of TGF-beta inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy", NATURE MATERIALS, vol. 11, no. 10, 2012, pages 895 - 905, XP055419588
SCHLINGENSIEPEN, K.-H. ET AL.: "Transforming growth factor-beta 2 gene silencing with trabedersen ( AP 12009) in pancreatic cance r", CANCER SCIENCE, vol. 102, no. 6, June 2011 (2011-06-01), pages 1193 - 1200, XP055451198, DOI: 10.1111/j.1349-7006.2011.01917.x
ALVAREZ, M. ET AL.: "Increased antitumor effects using IL-2 with anti-TGF-beta reveals competition between mouse NK and CDS T cells", THE JOURNAL OF IMMUNOLOGY, vol. 193, 7 June 2014 (2014-06-07), pages 1709 - 1716, XP055694834
SCHLINGENSIEPEN KH ET AL., CANCER SCI, vol. 102, 2011, pages 1193 - 200
See also references of EP 3854405A4
SCHLINGENSIEPEN, K.-H. ET AL.: "Transforming growth factor-beta 2 gene silencing with trabedersen ( AP 12009) in pancreatic cance r", CANCER SCIENCE, vol. 102, no. 6, June 2011 (2011-06-01), pages 1193 - 1200, XP055451198, DOI: 10.1111/j.1349-7006.2011.01917.x
ALVAREZ, M. ET AL.: "Increased antitumor effects using IL-2 with anti-TGF-beta reveals competition between mouse NK and CDS T cells", THE JOURNAL OF IMMUNOLOGY, vol. 193, 7 June 2014 (2014-06-07), pages 1709 - 1716, XP055694834
SCHLINGENSIEPEN KH ET AL., CANCER SCI, vol. 102, 2011, pages 1193 - 200
See also references of EP 3854405A4
Attorney, Agent or Firm:
KIM, Young-Shin (KR)
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